Carcinoma of the EsophagusSquamouscellcancerAdenocarcinoma
Carcinoma of the Esophagus
EssentialsofDiagnosis: Progressive dysphagia, initially during ingestion of solidfoods and later for liquids.Progressive weight loss and inanition.Classic radiographic outlines: irregular mucosal patternwith narrowing, with shelf-like upper border orconcentrically narrowed esophageal lumen.. Definitive diagnosis established by endoscopic biopsy orcytology
Essentials of Diagnosis • Progressive dysphagia, initially during ingestion of solid foods and later for liquids. • Progressive weight loss and inanition. • Classic radiographic outlines: irregular mucosal pattern with narrowing, with shelf-like upper border or concentrically narrowed esophageal lumen. • Definitive diagnosis established by endoscopic biopsy or cytology
General Considerations. Carcinoma of the esophagus constituted about 1% of allmalignant lesions and 6% of those of the gastrointestinaltract in the USA.Blacks have a fivefold higher incidence of squamous cellcarcinoma than whites, but the incidence ofadenocarcinoma among blacks is one-third that of whitesBoth lesions are more common among men, with amale-to-female ratio of 7:10 for adenocarcinoma and 3:4forsquamous celltumors.: The peak incidence is between ages 50 and 60 years
General Considerations • Carcinoma of the esophagus constituted about 1% of all malignant lesions and 6% of those of the gastrointestinal tract in the USA. • Blacks have a fivefold higher incidence of squamous cell carcinoma than whites, but the incidence of adenocarcinoma among blacks is one-third that of whites. • Both lesions are more common among men, with a male-to-female ratio of 7:10 for adenocarcinoma and 3:4 for squamous cell tumors. • The peak incidence is between ages 50 and 60 years
: Estimated new cases and deaths fromesophageal cancer in the United States in2009:New cases: 16,470Deaths: 14,530Esophagealcancer- ww.cancer.gov
• Estimated new cases and deaths from esophageal cancer in the United States in 2009: New cases: 16,470 Deaths: 14,530 - www.cancer.gov
Causes;Not ExactlyKnownmoteneictobacco and alcohol use [3o*more likely)exposuretolyedietis notprovento have affect buta wellbalanced oneisalways encouraged