8.5 Post-translational membrane insertion depends on leader sequences Tom22 20receptor T0rm56,7 Tom40 channel Figure 8.13 TOM proteins form receptor complex(es) that are needed for translocation across the mitochondrial outer membrane 清苇大当
Figure 8.13 TOM proteins form receptor complex(es) that are needed for translocation across the mitochondrial outer membrane. 8.5 Post-translational membrane insertion depends on leader sequences
8.5 Post-translational membrane insertion depends on leader sequences 2222.230 Tim17-23 channel?Intermembrane space Tim44 Hsp70 Matrix MGE Figure 8.14 Tim proteins form the complex for translocation across the mitochondrial inner membrane. 情華大当
Figure 8.14 Tim proteins form the complex for translocation across the mitochondrial inner membrane. 8.5 Post-translational membrane insertion depends on leader sequences
Cytosol 8.5 Post-translational 66686C1001046964866 membrane insertion depends on leader sequences 990 W99 Figure 8.15 Tim9-10 takes proteins from Inter membrane TOM to either TIM space complex,and Tim8- W址 13 takes proteins to Tim22-54. Tim17-23 Matrix Tim22-54 清菜大当
Figure 8.15 Tim9-10 takes proteins from TOM to either TIM complex, and Tim8- 13 takes proteins to Tim22-54. 8.5 Post-translational membrane insertion depends on leader sequences
Cytosol 8.5 Post-translational 1868068 membrane insertion depends on leader sequences Protein passes directly from TOM to Tim9-10 and then to TIM Intermembrane space Figure 8.16 A 10010614 translocating protein may be transferred directly from TOM to Tim22-54. 清菜大当 Tim 22-54 channel Matrix
Figure 8.16 A translocating protein may be transferred directly from TOM to Tim22-54. 8.5 Post-translational membrane insertion depends on leader sequences
● Signal for 8.6 A hierarchy of outer membrane sequences determines location within TOM receptor organelles TIM recepto Intemembrane space Figure 8.17 Mitochondria have receptors Outer membrane for protein transport in the outer and Signal for intermembrane space inner membranes.Recognition at the outer membrane may lead to transport through both receptors into the matrix, where the leader is cleaved.If it has a membrane-targeting signal,it may be re- exported 清第大当
Figure 8.17 Mitochondria have receptors for protein transport in the outer and inner membranes. Recognition at the outer membrane may lead to transport through both receptors into the matrix, where the leader is cleaved. If it has a membrane-targeting signal, it may be reexported. 8.6 A hierarchy of sequences determines location within organelles