b 绘 淡 The IGFIR- IC induces cell death. A) Comparison between the c
Table 1. Comparison of apoptosis, necrosis and paraptosis poptosIS Necrosis Paraptosis Morphology Nuclear fragmentation Apoptotic bodies Cytoplasmic vacu。 ation Mitochondrial Late welling Genomic effect TUNEL Usually nternucleosom. DNA fragmentation DEVD-cleaving activity Caspase-3 processing PARP cleavage (85-kDa +(50-to fragment) 62-kDa fragme Inhibition by zVAD. fnk p35 xIap Bcl Usually Actinomycin D Sometimes Cycloheximide Sometimes DEVD, Asp-Glu-Val-Asp: PARP, poly (ADP-ribose) polymerase
nerve cells dead cells nerve body CELL DEATH MATCHES nerve NUMBER cell OF NERVE CELLS axor TO NUMBER OF TARGET CELLS survival factor target cells released by target cells
A 1 mm