上海交通大学：《微生物学 Microbiology》课程教学资源（双语课件）Lecture 13.3 Metabolic Diversity（Catabolism of Organic Compounds）The anaerobic way of life：Fermentation and syntrophy 无氧生活 方式：发酵与互养

Question:Is this a fermentation process?Why do you think so? Propionigenium modestum catabolizes succinate under strictly anoxic conditions Sodium-extruding decarboxylase Na+ 3-4 Na+ Succinate2- Na+ ATPase A sodium-translocating ATPase produces ATP; Na+ CH2- sodium export is linked to ADP ATP +P1 0 Succinate2-0 the energy released by CCH2CH5 succinate Na+ O Propionate- decarboxylation.琥珀酸 HCO3 脱羧 (a) 2012 Pearson Education.Inc

Question: Is this a fermentation process? Why do you think so? Propionigenium modestum catabolizes succinate under strictly anoxic conditions A sodium-translocating ATPase produces ATP; sodium export is linked to the energy released by succinate decarboxylation. 琥珀酸 脱羧

13.17 Fermentations lacking substrate- level phosphorylation With certain substrates there is insufficient energy released to couple to ATP synthesis by substrate-level phosphorylation. How to support growth of an organism??? Catabolism of the substrate is linked to ion pumps that establish a proton or sodium gradient across the membrane. Example 1 Example 2 Chen Feng,Microbiology,SJTU

Chen Feng, Microbiology, SJTU 13.17 Fermentations lacking substrate￾level phosphorylation With certain substrates there is insufficient energy released to couple to ATP synthesis by substrate-level phosphorylation. How to support growth of an organism??? • Catabolism of the substrate is linked to ion pumps that establish a proton or sodium gradient across the membrane. Example 1 Example 2