Muscarinic receptor agonists o(2)Systemic use Dry mouth: radiotherapy Antidote for atropine poisoning
（2）Systemic use Dry mouth: radiotherapy Antidote for atropine poisoning Muscarinic receptor agonists
Muscarinic receptor agonists u 3. Adverse effects o( 1) Local(eye): pain, tears o(2)Systemic: secretion of exocrine glands, treated with atropine
3. Adverse effects （1）Local (eye): pain, tears （2）Systemic: secretion of exocrine glands, treated with atropine Muscarinic receptor agonists
Cholinoceptor antagonists
Cholinoceptor antagonists
Muscarinic receptor antagonists Vesicula (not yet Choline Choline 59 Choline transporter Presynaptic terminal ∵∴∵,;,r9hme Postsynaptic cell l。含 lon channels Second messengers (cAMP. IR. DAG, Ca") Cellular responses
Muscarinic receptor antagonists
Axon Hemicholinium ACCoA+ Choline Action sites of Nerve cholinoceptor antagonist Calcium channel ATP. P Hetero eceptor Presynaptic° Acetylcholine receptors VAMP 次 Botulinum TP. P SNAPS Choline Acetylcholinesterase Acn 升 Acetate 日 Other receptors
Action sites of cholinoceptor antagonist