(3)All the DNA viruses contain contiguous genome So do most RNA viruses. The genome of some RNA viruses are segmented to reduce the chance of error. NS d NS Inflenza virus-8 segments,ssRNA genome
Inflenza virus-8 segments, ssRNA genome ▶(3) All the DNA viruses contain contiguous genome； So do most RNA viruses. The genome of some RNA viruses are segmented to reduce the chance of error
(4)具有重叠基因Gene overlapping Also found in mitochondria and plasmid DNA Types of gene overlapping: one gene is completely lies in another gene; *partially overlapped; only one base overlapped between two genes;
▶(4) 具有重叠基因Gene overlapping Also found in mitochondria and plasmid DNA； Types of gene overlapping: ★ one gene is completely lies in another gene; ★ partially overlapped; ★ only one base overlapped between two genes;
mRNA Viral strand DNA synthesis A'translation H begins here mRN情 G 中X174 Complementary strand DNA synthesis Spacer DNA 3 L上sL Initiation*●● met leu leu pro
Discovery of overlapping genes 。1977年首先发现的，Sanger测定了X174核苷 酸序列，X174基因组由5386个核苷酸组成。 ·基因的产物都已被分离，它们所含的氨基酸已 远远超过了5386个核苷酸编码的量，将全部 DNA顺序和蛋白质的氨基酸顺序比较后发现了 重叠基因现象
Discovery of overlapping genes • 1977年首先发现的，Sanger测定了фX174核苷 酸序列，фX174基因组由5386个核苷酸组成。 • 基因的产物都已被分离，它们所含的氨基酸已 远远超过了5386个核苷酸编码的量，将全部 DNA顺序和蛋白质的氨基酸顺序比较后发现了 重叠基因现象
mRNA Vral strand DNA synthesis A'translation begins here mRN情 G 争X174 9 Complementary mRNA strand DNA synthesis Spacer DNA met his ala 5 AUGCCUACCCAUCCUUUUCCC万' LL」LcLL Initiation*e met leu leu pro