16.2 The retrovirus 3 life cycle involves RNA primer is removed transposition like 3 1111111 RNA is degraded,leaving fragments events to prime DNA synthesis 3' Strong stop plus strand DNA is synthesized 5 Plus strand DNA is transferred to other end of minus strand in secondjump Figure 16.7 Synthesis of 31 5 5 plus strand DNA requires a ustrand DNA synthesis is completed second jump 33 5 51 Minus strand DNA is completed 3 清菜大当 LTR LTR
Figure 16.7 Synthesis of plus strand DNA requires a second jump. 16.2 The retrovirus life cycle involves transposition like events
16.2 The retrovirus life cycle involves transposition like events Integrase generates 2 base recessed 3'ends in LTRs inrtesstaggered ends LTR LTR HHHHHHHHHH+升 HHHHHHHHHHHHHH Figure 16.9 Integrase HHHHHHHHH is the only viral protein required for the integration reaction,in 3 which each LTR loses 3 Integrase links recessed 3'ends ofLTR to staggered 5'ends oftarget 2 bp and is inserted between 4 bp repeats of target DNA. 清菜大当
Figure 16.9 Integrase is the only viral protein required for the integration reaction, in which each LTR loses 2 bp and is inserted between 4 bp repeats of target DNA. 16.2 The retrovirus life cycle involves transposition like events