UCLInflammation causes cholesterol redistributionbydiverting cholesterol from circulation to tissuecompartments
Inflammation causes cholesterol redistribution by diverting cholesterol from circulation to tissue compartments
JCLPartnersAcademicHealthhncaHn0JCLPartnersAcademicHealthSciencePartnershipRoyal FreeUCLHGOSHUCLMoorfields
UCLH GOSH UCL Moorfields Royal Free
UCLR&D:UCLEuropeanLeaders inResearch inClinicalMedicineGood strength22NobelPrize.4thrankedintheworldin Basic Science6000NHSHighest performing UKUniversityUniversityinBiomedicine (RAE)4000International Leaders inNeuroscienceResearch..200Growing ResearchAwardPortfolioInvestment in infrastructure,people and partnershipsStrongandestablishedR&Dplatformfor UCLPartners
2000 0 4000 6000 NHS University Highly Cited Publications Good strength in Basic Science Highest performing UK University in Biomedicine (RAE) International Leaders in Neuroscience Research. Growing Research Award Portfolio Investment in infrastructure, people and partnerships Strong and established R&D platform for UCLPartners R&D: UCL European Leaders in Research in Clinical Medicine 22 Nobel Prize. 4th ranked in the world
UCLChronic Renal DiseaseDiabetesOther inflammatory diseaseMOORHEAD(Cause)HypothesisMoorhead et al LancetVLDL↑ ↑1982VLDL remnants ↑Small dense LDL ↑Ruan etalHDLNature ReviewNephrology,2009InflammationAtherosclerosis/NAFL
VLDL VLDL remnants Small dense LDL HDL Chronic Renal Disease Diabetes Other inflammatory disease Atherosclerosis/NAFL (Cause) Inflammation MOORHEAD Hyp othesis Moorhead et al Lancet 1982 Ruan et al Nature Review Nephrology, 2009
UCLMesangial foam cellsGlomerular capillariesa siteforatherosclerosis*AB
Mesangial foam cells Glomerularcapillariesa siteforatherosclerosis* A B C