VARICELLA(CHICKENPOX)
VARICELLA (CHI CKENPOX)
OverviewPrimary infection with varicella-zoster virus (VzV)causes varicella (chickenpox)Varicella is characterized by the appearance onthe skin and mucous membranes of successsivecrops oftypical vesicles,generallyaccompanyedbya mild constitutionalreaction.The virus establishes latent infection indorsalroot ganglia; its reactivation causes herpes zoster(shingles)
Ove r view Primary infection with varicella-zoster virus (VZV) c a u s e s varicella (chickenpox). Varicella is characterized by the a p p ea ra nce on the skin a n d mu cou s memb ra n es of su ccesssive crop s of typical vesicles, generally a ccomp a n yed by a mild constitutionalreaction. The virus esta b lishes latent infection in dorsal root ganglia; its reactivation c a u s e s h erp es zoster (shingles)
ETIOLOGY
ETIOLOGYClassification: double-stranded DNAvirusthe viral genome encodes more than 70 proteinshuman herpesvirus;alpha herpesvirusSerotype: Only onebecause ofits similarities to the prototype for this group,which isherpes simplex virus (HSV)
ETI OLOGY Classification: double-stranded DNAvirus the viral genome encodes more than 70 proteins human herpesvirus; alpha herpesvirus Serotype: Only one becaus e of its similarities to the prototype for this group, which is herpes simplex virus (HSV)
ETIOLOGY Location: Patients respiratory secretionsBlood, herpes fluid. Characterization:Sensitive to heat , acid and disinfectant
• Loc a tion: Pa tients re s p ira tory s e c re tions , Blood, her p es fluid • Characterization: Sensitive to heat , acid and disinfectant ETI OLOGY