Transcription factors interact and bind to cis-controlelements andinteract with the basal transcription apparatusmRNAExpression1.Temporal2.Spatial3.Amplitudetf1tf2tf3tf4tf5tf6TranscriptionfactorBasaltranscriptionapparatusTranscriptionfactorbindingsitesorcis-controlelementsFig.21.512-16
Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display 12-16 Transcription factors interact and bind to Transcription factors interact and bind to cis-control control elements and interact with the basal transcription apparatus elements and interact with the basal transcription apparatus Fig. 21.5
Complex feed-forward and feed-back loops generatedbygeneregulatorynetworksTransientlocalized inputGene1Gene2aGene2bGene3Fig.21.612-17
Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display 12-17 Complex feed Complex feed-forward and feed forward and feed-back loops generated back loops generated by gene regulatory networks by gene regulatory networks Fig. 21.6