Chapter 11The Eukaryotic Chromosome13-1
Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display 13-1 The Eukaryotic Chromosome The Eukaryotic Chromosome Chapter 11 Chapter 11
Sectionsto study11.1ChromosomalDNAandproteins11.2 Chromosome structure and compaction11.3Chromosomalpackaging and gene expression11.4Replication of eukaryotic chromosomes11.5Chromosomesegregation1l.6Artificialchromosomes13-2
Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display 13-2 Sections to study Sections to study 11.1 Chromosomal DNA and proteins 11.1 Chromosomal DNA and proteins 11.2 Chromosome structure and compaction 11.2 Chromosome structure and compaction 11.3 Chromosomal packaging and gene expression 11.3 Chromosomal packaging and gene expression 11.4 Replication of eukaryotic chromosomes 11.4 Replication of eukaryotic chromosomes 11.5 Chromosome segregation 11.5 Chromosome segregation 11.6 Artificial chromosomes 11.6 Artificial chromosomes
Chromosome-The self-replicating genetic structures of cellscontaining the DNA that carries in its nucleotide sequence thelineararrayofgenes二果S36789101112341EB8828a5131415161718STHumanchromosomes19202122V十Humanmalekaryotype13-3
Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display 13-3 Human chromosomes Human male karyotype Chromosome Chromosome − The self The self-replicating genetic structures of cells replicating genetic structures of cells containing the DNA that carrie containing the DNA that carries in its nucleotide sequence the s in its nucleotide sequence the linear array of genes. linear array of genes
HEN:DecIsiontoduplicated?duplicateChromosomesTHEN:Decisionchromosomesandto entermitosischange shape andcentrosomesposition duringthe cell cycleProphaseMitosisInterphaseCOngoingproteinsynthesisMetaphaseandcellgrowthHave all.Telophase1chromosomesandarrived andcytokinesisaligned attheAnaphasemetaphaseplate?13-4
Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display 13-4 Chromosomes change shape and position during the cell cycle
Chromatin（染色质）-ThegenerictermforanycomplexofDNAand protein foundin a cell's nucleusChromonemafiberLinkerhistonesNLong rangefiber-fiberShortrangeinteractionsinternucleosomainteractions30nmfiberG1chromatidBeads-on-a-stringNucleosomeCore histoneDNANtail domain13-5
Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display 13-5 Chromatin Chromatin (染色质)− The generic term for any complex of DNA The generic term for any complex of DNA and protein found in a cell and protein found in a cell’s nucleus. s nucleus