1.Definitions: topoisomerase, ribozyme, double helix, DNA denaturation, Tm, linking number, pseudoknot. 2.What are the structural differences between DNA and RNA? How the structural properties of DNA and RNA determine their distinct biological functions

武汉大学生命科学学院：《分子生物学》英文版 Intro 课程介绍

Gene,5/e--- Watson et al.(2004) Part: Chemistry and Genetics Part ll: Maintenance of the Genome Part Ill: Expression of the Genome Part IV: Regulation Part V: Methods

Molecular Biology of the Gene, 5/E -- Watson et al. (2004) Part I: Chemistry and Genetics Part: Maintenance of the Genome Part Ill: Expression of the Genome Part IV: Regulation Part V: Methods

Similarity of regulation between eukaryotes and prokaryote 1. Principles are the same: signals, activators and repressors, recruitment and allostery, cooperative binding 2. Expression of a gene can be regulated at the similar steps, and the initiation of transcription is the most pervasively regulated step

Expression of many genes in cells are requlated Housekeeping genes expressed constitutively, essential for basic processes involving in cell replication and growth. Inducible genes expressed only when they are activated by inducers or cellular factors

Part III: Expression of the Genome Ch 12: Mechanisms of Transcription Ch 13: RNA Splicing Ch 14: Trans lation Ch 15: The Genetic Code

Molecular Biology of the Gene, 5/E---Watson et al. (2004) Part: Chemistry and Genetics Part ll: Maintenance of the Genome Part Ill: Expression of the Genome Part IV: Regulation Part V: Methods

Plant Biotechnology Traditional Recombinant crossbreeding DNA techniques Plasmid insertion Gene

Introduction The nervous tissue of animals responds to stimuli within and outside of the body. Incoming information is integrated and a response is made. The response is muscle contraction or secretion by a gland. The end hydra result is the maintenance of body functions or homeostasis