Actinomycetes(放线菌)
Actinomycetes (放线菌 )
Actinomycosis(放线菌病)
Actinomycosis （放线菌病）
Mechanism of penicillin Binding to transpeptidase and then inhibiting the formation of peptidoglycan cross-links in the bacterial cell wall
Mechanism of penicillin • Binding to transpeptidase and then inhibiting the formation of peptidoglycan cross-links in the bacterial cell wall
Peptidoglycan(肽聚糖) is a 3D molecule Polysaccharide chains Peptidoglycan S-layer Lipoteichoic acid Neutral polysaccharide Teichoic acid (the glyean portion) NAG NAG NAM NAG NAG NAM NAM NAG NAM NAG NAG NAM NAM NAG NAM NAM Peptide cross-links (the peptide portion) Cross links are both horizontal and vertical between glycan chains stacked atop one another
Peptidoglycan（肽聚糖） is a 3D molecule Cross links are both horizontal and vertical between glycan chains stacked atop one another
Penicillins(青霉素类) 1青霉素悔作用部位 S、CH 2酰胺酶作用部位 R一C-NH一CH·CHC IBIACH A噻唑环 0=0NCH900H BB-内酰胺环 青霉素 酰胺酶 CH CH R-CF+WH2—CH·CIC R-C-NH-CH-CHC IICH O-C-N-CH-COOH O-C N-CH COOH 6-氨基青霉烷酸 OH H R+ 青霉噻唑酸
Penicillins （青霉素类 ）