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细胞通讯(cellcommunication)是细胞间或细胞内通过高度精确和高效地发送与接收信息的通讯机制,对环境作出综合反应的细胞行为。17
17 细胞通讯(cell communication) 是细胞间或细胞内通过高度精确和高效地发送与接收 信息的通讯机制,对环境作出综合反应的细胞行为
几个容易混淆的概念近年来,由于细胞通信在医学尤其是揭示癌症方面的重要性,使这一领域的研究十分活跃,文献和著作非常的多,不同的作者往往使用不同的名词来描述细胞的信息传递现象,虽然这些名词很相近,但是其内涵和外延不尽相同,现解释如下:细胞通讯(cellcommunication)指一个细胞发出的信息通过介质传递到另一个细胞产生相应反应的过程。Anyof severalwaysinwhichlivingcells of an organism communicatewith one another, whether bydirect contact between cells or by means of chemical signalscarried by neurotransmitter substances, hormones, and cyclicamp.细胞识别(cellrecognition)指细胞与细胞之间通过细胞表面的信息分子相互作用,从而引起细胞反应的现象。Interactionbetweencells that is possibly dependent upon specific adhesion.Since themechanismis not entirely clearin most cases,theterm should beused with caution.18
18 近年来,由于细胞通信在医学尤其是揭示癌症方面的重要性,使这一领域的 研究十分活跃,文献和著作非常的多,不同的作者往往使用不同的名词来描 述细胞的信息传递现象,虽然这些名词很相近,但是其内涵和外延不尽相同, 现解释如下: 细胞通讯(cell communication)指一个细胞发出的信息通过介质传递到另一 个细胞产生相应反应的过程。Any of several ways in which living cells of an organism communicate with one another, whether by direct contact between cells or by means of chemical signals carried by neurotransmitter substances, hormones, and cyclic amp. 细胞识别(cell recognition)指细胞与细胞之间通过细胞表面的信息 分子相互作用,从而引起细胞反应的现象。Interaction between cells that is possibly dependent upon specific adhesion. Since the mechanism is not entirely clear in most cases, the term should be used with caution. 几个容易混淆的概念
信号传导(cellsignaling发放)细胞合成和释放信号分子,将信息传递给其它细胞。Releasebyonecellof substancesthattransmitinformation to other cells信号转导(signaltransduction)指外界信号(如光、电、化学分子)与细胞细胞表面受体作用,通过影响细胞内信使的水平变化,进而引起细胞应答反应的一系列过程。Thecascade ofprocesses by which an extracellular signal (typically a hormoneor neurotransmitter)interacts with a receptor at the cell surfacecausing a change in the level of a second messenger (for examplecalcium or cyclic AMP)and ultimatelyeffects a change in thecell's functioning (for example, triggering glucose uptake, orinitiating cell division).Can also be applied to sensory signaltransduction, eg. of light at photoreceptors.19
19 信号传导(cell signaling发放)细胞合成和释放信号分子,将信 息传递给其它细胞。Release by one cell of substances that transmit information to other cells. 信号转导(signal transduction)指外界信号(如光、电、化学 分子)与细胞细胞表面受体作用,通过影响细胞内信使的水平 变化,进而引起细胞应答反应的一系列过程。The cascade of processes by which an extracellular signal (typically a hormone or neurotransmitter) interacts with a receptor at the cell surface causing a change in the level of a second messenger (for example calcium or cyclic AMP) and ultimately effects a change in the cell's functioning (for example, triggering glucose uptake, or initiating cell division). Can also be applied to sensory signal transduction, eg. of light at photoreceptors