HUMAN PHYSIOLOGY PPT Presentation by Chen Qi Chapter 8 Urinary Physiology Physiological Department of Medical College, Yangzhou University
General introductionofkidney1Renal Functions1.1 urine formationexcrete wastes ,maintain H,O, ions, acid-base balance1.2 secret hormones : renin, 1,25-vitaminD3, erythropoietinPPTPresentationbyChenQi,YangzhouUniversity
2.Renal structure2.2 Cortical nephron and juxtamedullary nephronconcentration and dilution of urineurine formation2.3 Juxtaglomerular apparatus (JGA) juxtaglomerular cells : secret reninmacular densa : regulate renin secretionPPTPresentationbyChenQi,YangzhouUniversity
3. Renal blood flow3.1Characteristics3.2Regulation1)Autoregulationdefinition:Bp(80-180mmHg)→RPFconstant② significance :under physiological condition, keep RPF and thenGFR constant, to make sure wastes canbeexcreted?mechanismsPPTPresentationbyChenQi,YangzhouUniversity
2) nervous-hormonal regulatior①Bp<80mmHg→urineIlsympathetic nerves @ ; NE, E, angiotensinII 个② significance : under exercise or severe hemorrhage, spares alarge amount of blood for active or important organsPPTPresentationbyChenQi,YangzhouUniversity