Aromatic Amines Amino group is bonded to a benzene ring. Parent compound is called aniline. NH2 N(CH2CH3)2 CH2CH3 CH aniline 2-ethylaniline N,N-diethylaniline 4-methylaniline or o-ethylaniline or p-toluidine Copyright 2010 Pearson Prentice Hall,Inc
Aromatic Amines Amino group is bonded to a benzene ring. Parent compound is called aniline
Heterocyclic Amines The nitrogen is assigned the number 1. H H CH3 aziridine pyrrole pyrrolidine 1-methylpyrrolidine imidazole indole (N-methylpyrrolidine) CH3 pyridine 2-methylpyridine piperidine Pyrimidine purine Copyright2010 Pearson Prentice Hall,Inc
Heterocyclic Amines The nitrogen is assigned the number 1
Sec 2 Properties Of Amines ■Structure ■Pyramidal inversion ■Basicity ■Physical properties
Sec 2 Properties Of Amines Structure Pyramidal inversion Basicity Physical properties
Structure of Amines Nitrogen is sp3 hybridized with a lone pair of electrons in an sp3 orbital. N…H N…CH3 H3C H107° CH3 108 ammonia trimethylamine 氨的结构 三甲胺的结构 electrostatic potential map of trimethylamine
Structure of Amines Nitrogen is sp3 hybridized with a lone pair of electrons in an sp3 orbital. 氨的结构 三甲胺的结构
脂肪族胺」 N原子呈不等性sp3杂化态，其中一 个sp3杂化轨道上有一对孤电子对，没有参与成 键，可接受+形成配位键。另外，氨分子中的 H原子被胺分子中的一R取代，一R的+I效应虽 然使N原子接受质子的能力增强
脂肪族胺 N原子呈不等性sp3杂化态，其中一 个sp3杂化轨道上有一对孤电子对，没有参与成 键，可接受H+形成配位键。另外，氨分子中的 H原子被胺分子中的—R取代，—R的+I效应虽 然使N原子接受质子的能力增强