The budding yeast Saccharomyces cerevisiaeCell polarity(Cytoskeleton,vesiculartransportChromosomeorganizationNuclear structureAgeingCell cycleregulationOrganellebiogenesisMitosisMeiosisCytokinesis20-6
20-6 Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display The budding yeast The budding yeast Saccharomyces Saccharomyces cerevisiae cerevisiae Cell cycle regulation Mitosis Meiosis Cell polarity (Cytoskeleton, vesicular transport) Cytokinesis Chromosome organization Nuclear structure Ageing Organelle biogenesis
The fruitflyDrosophilaFertilizationmelanogasterOAdultREmbryoPupa31/2-41/2days1dayinpupalstageFirstinstarlarva21/2-3daysDrosophila life cycle1 dayThirdSecondinstarlarva1 dayinstarlarva20-7
20-7 Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display The fruitfly fruitfly Drosophila Drosophila melanogaster melanogaster
All living forms arerelated ...Evolution has conserved basic strategies of development acrossmulticellulareukaryotes.The eyes ofinsects and mammals havea common ancestor.eyeless gene in fruit fliesPax-6 gene in miceAniridiageneinhumansommatidiaFig.1.720-8
20-8 Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display All living forms are related All living forms are related . ommatidia Fig. 1.7 Evolution has conserved basic strategies of development across Evolution has conserved basic strategies of development across multicellular multicellular eukaryotes. eukaryotes. The eyes of insects and mammals have a common ancestor. The eyes of insects and mammals have a common ancestor. eyeless eyeless gene in fruit flies gene in fruit flies Pax-6 gene in mice gene in mice Aniridia Aniridia gene in humans gene in humans
Wild-typeWild-typefruit flymouse fetuseyeless mutantpax-6 mutantof fruit flyFig.18.220-9
20-9 Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display eyeless mutant of fruit fly Wild-type mouse fetus pax-6 mutant Fig. 18.2 Wild-type fruit fly
EctopicredeyetissueWild-typefruitflyEctopicredeyetissueEctopic expression of eyeless gene20-10
20-10 Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Ectopic expression of eyeless gene Wild-type fruit fly