Professor Arne Tiselius in his chromatography laboratory in the early 1950s. In some experiments he used quartz columns and UV-light to follow the migration of protein zones using a television monitor. Photo:Uppsala Bild/Upplandsmuseet
Professor Arne Tiselius in his chromatography laboratory in the early 1950s. In some experiments he used quartz columns and UV-light to follow the migration of protein zones using a television monitor. Photo: Uppsala Bild / Upplandsmuseet
1.2.Enzyme Engineering >1894 Japan amylase first commercial enzyme 1953 Grubhofer and Schleith immobilization of enzyme 1969 immobilized enzyme in industry to produce amino acid(Japan) The system of enzyme and viable cell immobiliton was coupled amino acid,organic acid,ribonucleotide and antibiotics Novel biotechnologies were applied in enzyme engineering cell fusion and DNA recombination used to improve the strain of enzyme
1.2. Enzyme Engineering ➢ 1894 Japan amylase（first commercial enzyme ） ➢ 1953 Grubhofer and Schleith immobilization of enzyme 1969 immobilized enzyme in industry to produce amino acid(Japan ) ➢ The system of enzyme and viable cell immobiliton was coupled amino acid, organic acid, ribonucleotide and antibiotics ➢ Novel biotechnologies were applied in enzyme engineering cell fusion and DNA recombination used to improve the strain of enzyme
1.3.Genetic Engineering 1974.US Boyer and Cohen recombinant DNA 1976.Genentech first biotechnology company was established 1977.Boyer hGH 1977.W.Gilbert（1978年获诺贝尔化学奖) insulin
1.3. Genetic Engineering 1974. US Boyer and Cohen recombinant DNA 1976. Genentech first biotechnology company was established 1977. Boyer hGH 1977. W.Gilbert（1978年获诺贝尔化学奖） insulin