Chapter 5 Reactor Design and Instrumentation
Reactor Design and Instrumentation Chapter 5
PROMOTCS Exhaust air XANTHAN GUM treetment i 060 动 TISSUE CULTURE Liquid feeds Inoculum ANTITUMOR AGENTS CITRIC ACID reector 00酒0 Ammonia MONOCLONAL ANTIBODY Gucose 2 Disintegration MSG INOSINB Extraction 动前 VACCINES ⑧ 萌店 ANTIBIOTICS 动咖 WASTE WATER TREATMENT DIAG.ENZYMES 01i0 PEG Salt Phase separation SINGLE CELL PROTEIN .DNA 前动 PEG+ Air 的 harvest sterilisation Ultrafiltration STEROIDS IND.BNZYMES Product Buffer 0i的i2 前动 Freeze 0.01 0.1 1 10 drying 100 10001000100000 Bioreactor Size m3 The bioreactor and auxiliary equipment used for production of the intracellular enzyme B-galactosidase from E.coli 1g. Biotecholoy Products and Bioreactor Size
5.1.The conventional stirred tank reactor Dt Parameter Symbol Dimension Reactor diameter Dt Liquid height HL 2-5Dt Di Impeller diameter Di 0.33-0.5Dt Impeller distance I 1-1.5Di Baffle width Wb 0.08Dt △ Advantages of Impeller STR Baffle Sparger Air The conventional stirred tank reactor (STR)and some standard dimensions
5.1. The conventional stirred tank reactor Advantages of STR ?
Side view:Flow pattern: Top view: Disc turbine Open turbine 露 图 828 Propeller ☏ Common stirrer types used in bioreactors (Left hands figures illustrate the liquid flow pattern)
Common stirrer types used in bioreactors (Left hands figures illustrate the liquid flow pattern)
Some standard dimensions of the STR B0.2B D=T/3,H0=1.5-2.0T, 宝￥ B=0.1T,ho=0.25T, S=2-3D,C=D
D=T/3, H0=1.5-2.0T, B=0.1T, h0=0.25T, S=2-3D, C=D Some standard dimensions of the STR