JOINT TISSUES REPARATIVE PROCEDURES Art. cart. Microfracture, osteochondral plugS, articular chondrocyte implantation Tiss, engr. cart; Collagen matrices ACL Tendon autografts Meniscus Suture, meniscal allografts Collagen matrices
JOINT TISSUES JOINT TISSUES REPARATIVE PROCEDURES REPARATIVE PROCEDURES Art. Cart. Art. Cart. Microfracture, osteochondral Microfracture, osteochondral plugs, articular chondrocyte articular chondrocyte implantation implantation [Tiss. engr. cart.; . cart.; Collagen matrices] Collagen matrices] ACL Tendon autografts Tendon autografts Meniscus Meniscus Suture, meniscal allografts Suture, meniscal allografts [Collagen matrices] [Collagen matrices]
JOINT TISSUES Tissue Cell round/ Loading Type Type Lac. Coll. PG Vasc Heal. Art. Cart, Comp. Hyal Chond. Yes II ++ 0 0 Cart Meniscus C/T Fibro-Fibro- Yes I 0/+ 0* 0 Cart. chond ACL Tens. fibrous fibro- no 000 Tissue blast 兴 Inner third 兴Mid- substance
JOINT TISSUES JOINT TISSUES Tissue Cell Round/ Loading Loading Type Type Lac. Coll. PG Vasc .Heal. Art. Cart. Art. Cart.Comp. Hyal . Chond .Yes II +++ 0 0 Cart. Meniscus Meniscus C/T Fibro - Fibro - Yes I 0/+ 0* 0 Cart. Chond . ACL Tens. Fibrous Fibrous Fibro - No I 0 0** 0 Tissue blast * Inner third * Inner third ** Mid ** Mid -substance substance
ARTICULAR CARTILAGE Chondrocytes Extracellular matrix ater 66-78% Organic material 22-34 Proteoglycan 22-38% collagen type II 48-62 Fibronectin Other matrix proteins 05-15%
ARTICULAR CARTILAGE ARTICULAR CARTILAGE Chondrocytes Chondrocytes Extracellular matrix Extracellular matrix Water 66 -78% Organic material Organic material 22 -34% Proteoglycan Proteoglycan 22 -38% Collagen type II Collagen type II 48 -62% Fibronectin & Fibronectin & Other matrix proteins Other matrix proteins 05 -15%
Human Knee from Patient with rheumatoid Arthritis Image removed due to copyright considerations
Human Knee from Knee from Patient with Patient with Rheumatoid Rheumatoid Arthritis Arthritis Image removed due to copyright considerations