BackgroundDiseaseburderDefntoEtiology of diarrheaInfectivefactors-Non-infective factorsPathogenesis of viral diarrheaPathogenes s ofentrotoxinic diarrheaPathgenesisofentromvasivediarrheaClinical manifestationsdehydratiometabolicacidosiclews.ofdiaonosisfordiarrheaTreatment of diarrheaFluidtheraAssessment of dehydrationReplacementEtiology of Diarrheainfantilediarrhea Dr.zhanxueChildren's Hospital16
Etiology of Diarrhea infantile diarrhea Dr.zhanxue Children's Hospital 16 Bac kground Disease burden Definition Etiology of diarrhea - Infective fac tors - Non-infective fac tors Pathogenesis of viral diarrhea Pathogenesis of entrotoxinic diarrhea Pathogenesis of entroinvasive diarrhea Clinical manifestations -dehydration, metabolic acidosis. Clews of diagnosis for diarrhea Treatment of diarrhea Fluid therapy Assessment of dehydration Replac ement
Etiology ofDiarrheaNon-infectiveInfectiveAllergicVirusesSymptomaticBacteriaInappropriatefeedingParasitesFood intoleranceFungi(lactose)Climate..rantilediarrhea Drzhanxue17Children's Hospital
infantile diarrhea Dr. Children's Hospi Etiology of Diarrhea Non-infective Infective Viruses Bacteria Par asites Fungi Allergic Symptomatic Inappropriate feeding Food intolerance (lactose) zhanxue Climate. tal 17
Etiology ofDiarrheaViralEnteropathogensViral enteropathogens cause most illnesses inpediatric population.Rotavirus (mornthan 50%acutediarrhea)otherssuch as Enteric adenovirus,AstrovirusNorwalk virus..infantilediarrhea Dr.zhanxue18Children's Hospital
Viral Enteropathogens Viral enteropathogens cause most illnessesin pediatric population. □ Rotavirus (morn than 50% acute diarrhea) □ others: such as Enteric adenovirus,Astrovirus, Norwalk virus. infantile diarrhea Dr.zhanxue Children's Hospital 18 Etiology of Diarrhea
Etiology ofDiarrheaRotavirusAdenovirus88infantile diarrhea Dr.zhanxue19Children's Hospital
Rotavirus Etiology of Diarrhea Adenovirus infantile diarrhea Dr.zhanxue Children's Hospital 19
Etiology ofDiarrheaBacterialEnteropathogensThe secondmost commoncauseofi childhooddiarrhea,justnext tothe viral enteropathogensEscherichia coli二Campylobacter jejuni口Shigella species福SalmonellatyphimuriumYersiniaenterocoliticaStaphylococcusaureusClostridium difficileVibrio choleraentile diarrhea Drzhanxue20Children's Hospital
The second most common cause of childhood diarrhea, justnext to the viralenteropathogens □ Escherichia coli □ Campylobacter jejuni □ Shigellaspecies □ Salmonella typhimurium □ Yersinia enterocolitica □ Staphylococcusaureus □ Clostridium difficile □ V ibrio cholerainefantile diarrhea Dr.zhanxue Children's Hospital 20 Bacterial Enteropathogens Etiology of Diarrhea