Diseases of the blood in Children 血液系统疾病 Associated Professor Gao Yijing Children s Hospital, Fudan University 复旦大学附属儿科医院
Associated Professor Gao Yijing Children`s Hospital, Fudan University Diseases of the Blood in Children 血液系统疾病
Diseases of the blood in children Anemias Nutritional anemias(Iron deficiency iron) Hereditary spherocytosis Glucose-6-phosphate dehydrogenase(G-6-PD) deficiency Thalassemia Bleeding disorders(Hemorrhagic diseases) ITP Hemophilia Neoplastic diseases 回复旦大学上海医学院儿科学系
Diseases of the Blood in Children • Anemias Nutritional anemias (Iron deficiency iron) Hereditary spherocytosis Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency Thalassemia • Bleeding disorders (Hemorrhagic diseases) ITP Hemophilia • Neoplastic diseases
Development of the Hematopoietic System Blood formation first can be recognized as early as 3rd wk after conception By 2 mo active hematopoiesis is established in the liver which is the main site of blood formation during the middle portion of fetal life After about 6 mo hematopoiesis shifts gradually to the medullary spaces, and by birth most blood formation normally takes place in bone marrow Extramedullary hematopoiesis 回复旦大学上海医学院儿科学系
Development of the Hematopoietic System • Blood formation first can be recognized as early as 3rd wk after conception • By 2 mo active hematopoiesis is established in the liver, which is the main site of blood formation during the middle portion of fetal life • After about 6 mo hematopoiesis shifts gradually to the medullary spaces, and by birth most blood formation normally takes place in bone marrow Extramedullary hematopoiesis
Hematologic Values During Infancy and Childhood Normal ranges for peripheral blood counts vary significantly with age Red blood cells Physiologic anemia Hemoglobin White blood cells 回复旦大学上海医学院儿科学系
Hematologic Values During Infancy and Childhood • Normal ranges for peripheral blood counts vary significantly with age Red blood cells Physiologic anemia • Hemoglobin • White blood cells
Anemia A reduction of the red blood cell mass or hemoglobin concentration below the range of values occurring in healthy persons 回复旦大学上海医学院儿科学系
Anemia A reduction of the red blood cell mass or hemoglobin concentration below the range of values occurring in healthy persons