幼年性类风湿性关节炎(JRA Juvenile rheumatoid arthritis 儿科医院邬惊雷
幼年性类风湿性关节炎 (JRA) Juvenile Rheumatoid Arthritis 儿科医院 邬惊雷
是一种少年儿童常见的结缔组织病 One of the most common connective tissue diseases of children 以慢性关节炎(滑膜炎)为主要特点 Characterized by chronic arthritis(synovitis of the joints) 多脏器受累,如肝脾肿大、淋巴结肿大、浆膜 炎(心包积液)等 Visceral involvement such as hepatosplenomegaly, lym phadenopathy and serositis(pericardial effusion)
是一种少年儿童常见的结缔组织病 One of the most common connective tissue diseases of children 以慢性关节炎(滑膜炎)为主要特点 Characterized by chronic arthritis (synovitis of the joints) 多脏器受累，如肝脾肿大、淋巴结肿大、浆膜 炎(心包积液)等 Visceral involvement ,such as hepatosplenomegaly, lymphadenopathy and serositis (pericardial effusion)
分类 Classification 全身型 systemic-onset disease 多关节型:5个或以上关节受累 Polyarthritis: 5 or more inflamed joints 少关节型:5个以下关节受累 Oligoarthritis: <5 inflamed joints
分类 Classification 全身型 systemic-onset disease 多关节型:：5个或以上关节受累 Polyarthritis:5 or more inflamed joints 少关节型：5个以下关节受累 Oligoarthritis: < 5 inflamed joints
流行病学 Epidemiology 发病率约113/10万 Overall prevalence approximately 113/100,000 约占住院0.1%-0.15% Accounts for about 0. 1%0-0.15% hospitalizations 女性发病较多 Females affected more frequently than males
流行病学Epidemiology 发病率约113/10万 Overall prevalence approximately 113/100,000 约占住院0.1%-0.15% Accounts for about 0.1%-0.15% hospitalizations 女性发病较多 Females affected more frequently than males
病因 Etiology 病因尚不清楚,可能与下列因素有关 Etiology is unknown, maybe related to the follows 免疫遗传易感性 Immunogenetic suseptibility 外源性触发因素(病毒感染) External triggers (virus infection)
病因 Etiology 病因尚不清楚,可能与下列因素有关: Etiology is unknown，maybe related to the follows: 免疫遗传易感性 Immunogenetic suseptibility 外源性触发因素 (病毒感染） External triggers （virus infection)