Normal bases Modified bases 7.3 tRNA contains modified bases that influence its pairing Uridine Ribothymidine(D Dihydrouridine(D)Pseudouridine (u)4thiouridine (S U) properties Figure 7.6 All of 5-methyloyfidine CH OL-CHE the four bases in tRNA can be Adenosin modified. 9 NH COOCH 清苇大兰 Guanosine 7-methylguanosine Queuosine (Q) Wyosine(
Figure 7.6 All of the four bases in tRNA can be modified. 7.3 tRNA contains modified bases that influence its pairing properties
7.3 tRNA contains modified bases that influence its pairing Sugar properties Cytosine Inosine Sugar Figure 7.7 Modification to Sugar inosine allows Uracil pairing with U,C. Inosine Sugar and A. sugar Adenine Inosine Sugar 情莘大兰
Figure 7.7 Modification to inosine allows pairing with U, C, and A. 7.3 tRNA contains modified bases that influence its pairing properties
One bond is not enough 7.3 tRNA contains modified bases that influence its pairing properties Sugar S Thiouracil H-N Guanine Sugar Figure 7.8 2-thiouracil pairs only with A Modification to 2- CH3 thiouridine restricts pairing to A alone because only one H- Sugar bond can form with G Thiouracil Adenine 清莘大当 Sugar
Figure 7.8 Modification to 2- thiouridine restricts pairing to A alone because only one Hbond can form with G. 7.3 tRNA contains modified bases that influence its pairing properties