7.2 Codon-anticodon recognition involves wobbling Wobble hypothesis accounts for the ability of a tRNA to recognize more than one codon by unusual (non-G C non-A T)pairing with the third base of a codon. 情莘大当
Wobble hypothesis accounts for the ability of a tRNA to recognize more than one codon by unusual (non-G C, non-A T) pairing with the third base of a codon. 7.2 Codon-anticodon recognition involves wobbling
7.2 Codon-anticodon recognition involves wobbling UUU UCU UAU UGU UUC ucc UAC UGC UUA UCA UAA UGA UUG UCG UAG UGG CUU CCU CAU CGU cuC ccc CAC CGC Figure 7.3 Third bases CUA CCA CAA CGA CUG cCG CAG CGG have the least influence AUU ACU AAU AGU AUC ACC AAC AGC on codon meanings AUA ACA AAA AGA AUG ACG AAG AGG Boxes indicate groups GUU GCU GAU GGU GUC Gcc GAC GGC GUA GCA GAA GGA of codons within which GUG GCG GAG GGG third-base degeneracy Third base relation ship Third bases Number with same of codons ensures that the meaning third base irrelev ant U,C,A,G 32 meaning is the same. purines differ UorC 14 from pyrimidines AorG 10 unique U,C,A 3 definitions G only 2 清苇大兰
Figure 7.3 Third bases have the least influence on codon meanings. Boxes indicate groups of codons within which third-base degeneracy ensures that the meaning is the same. 7.2 Codon-anticodon recognition involves wobbling
Standard base pairs occur at all positions 7.2 Codon-anticodon recognition involves wobbling Cytosine Guanine ugar Figure 7.4 Wobble in base pairing allows G-U Uracil pairs to form between Adenine Sugar the third base of the G-U wobble pairing occurs only at third codon position codon andand the first base of the anticodon. Uracil N Guanine suar 情莘大当
Figure 7.4 Wobble in base pairing allows G-U pairs to form between the third base of the codon and and the first base of the anticodon. 7.2 Codon-anticodon recognition involves wobbling
7.2 Codon-anticodon recognition involves wobbling Base in First Base(s)Recognized Position of in Third Position of Anticodon Codon U AorG G only U only G C or U Figure 7.5 Codon-anticodon pairing involves wobbling at the third position. 清苇大当
Figure 7.5 Codon-anticodon pairing involves wobbling at the third position. 7.2 Codon-anticodon recognition involves wobbling
7.3 tRNA contains modified bases that influence its pairing properties Modification of DNA or RNA includes all changes made to the nucleotides after their initial incorporation into the polynucleotide chain. 情莘大当
Modification of DNA or RNA includes all changes made to the nucleotides after their initial incorporation into the polynucleotide chain. 7.3 tRNA contains modified bases that influence its pairing properties