Anemias 中国医科大学附属第一医院血液科李艳
Anemias 中国医科大学附属第一医院血液科 李艳
CUFS(造血干C、红系祖C) proerythroblast (原始RBC) Basophilic normoblast(早幼RBC) Polychromatic normoblast(中幼RBC) Orthochromatic normoblast(晚幼RBC)此阶段脱 核进入血循环 Reticulocyte(网织RBC) 经特殊染色见到丝状或网状结构,保留残余线粒体 和核糖,仍有继续合成Hb的能力(从早幼RBC开始) erythrocyte
CUF-S (造血干C、红系祖C) ↓ proerythroblast （原始RBC） ↓ Basophilic normoblast （ 早幼RBC） ↓ Polychromatic mormoblast（中幼RBC） ↓ Orthrochromatic normoblast （晚幼RBC）此阶段脱 核进入血循环 ↓ Reticulocyte （网织RBC） 经特殊染色见到丝状或网状结构, 保留残余线粒体 和核糖，仍有继续合成Hb的能力（从早幼RBC开始） ↓ erythrocyte
Definition a reduction below normal in the concentration of hemoglobin, the mass of red blood cells andor the hematocrit in the blood In men Hb 120g/L RBC≤4.5×1012L HcT<0.42 In women Hb≤110g/L RBC<40×1012L HCT<0.37
Definition • A reduction below normal in the concentration of hemoglobin , the mass of red blood cells and/or the hematocrit in the blood. In men Hb < 120g/L RBC <4.5×1012/L HCT <0.42 In women Hb < 110g/L RBC<4.0 ×1012/L HCT<0.37
Factors influencing Hb concentration Sex A ge Altitude Alterations in plasma volume
Factors influencing Hb concentration Sex Age Altitude Alterations in plasma volume
★ Classification Morphologic classification Type MCV(um) MCH(PG)MCHC(% Diagnosis Macrocytic 100 >32 32-35 Megaloblastic anemla Normocytic 80-100 26-32 32-35 AA, HA, Acute posthemorrhagic anemla Microcytic <80 <26 <32 DA Sideroblastic anemia Thalassem ias
★Classification Morphologic classification Type MCV(um) MCH(PG) MCHC(%) Diagnosis Macrocytic ＞100 ＞32 32-35 Megaloblastic anemia Normocytic 80-100 26-32 32-35 AA, HA, Acute posthemorragic anemia Microcytic ＜80 ＜26 ＜32 IDA, Sideroblastic anemia Thalassemias