a The intensity of the poisoning effects depends on 1. the dose 2 the route of administration 3. individual differences 4. synergistic effect
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Administrated in different way, the poisoning effects can be different a Intravenous injection introduces a poison directly into the bloodstream which results in faster action than the oral administration In general, the lethal dose of a poison by injection is much lower than by oral administration Amygdalin is non-toxic when injected, but is toxic when taken orally
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The intensity of the poisoning effects depends on 1 the dose 2. the route of administration 3 individual differences ■Age, gender Health conditions Tolerance a Sensitivity 4. synergistic effect
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■To| erance A person accustomed to taking a drug, or who has been exposed to low doses of a poison over a period of time may be able to tolerate far more than the usual lethal dose
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Sensitivity difference As differences exist between individuals in the amount of metabolic enzymes, a given dose of a particular drug that may cause predictable results in most individuals may have serious or even lethal effects in another individual
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