EM of normal red blood cells
12 EM of normal red blood cells
Lift Span of Red Cells >Erythrocytes lack a nucleus and mitochondria >(they get energy from anaerobic(but not aerobic) respiration) >Life span: about 120 days >destroyed by phagocytic cells in the liver spleen and bone marrow 13
13 Lift Span of Red Cells ➢Erythrocytes lack a nucleus and mitochondria ➢ (they get energy from anaerobic (but not aerobic) respiration). ➢Life span: about 120 days ➢destroyed by phagocytic cells in the liver, spleen and bone marrow
Physical and Chemical Properties of the red cells ◆ Hematocrit ◆ Function Material for the production ◆ Erythropoiesis 14
14 Physical and Chemical Properties of the Red Cells Hematocrit Function Material for the production Erythropoiesis
Hematocrit > Concept: The percentage of blood volume occupied by the packed red blood cell volume >Normal range: man, 40%0-50%. Women 37%-48 15
15 Hematocrit ➢Concept: The percentage of blood volume occupied by the packed red blood cell volume ➢Normal range: man, 40% - 50%, Women 37% - 48%
MEASUREMENT OF HAEMATOCRIT The haematocrit ratio(Ht) is the proportion of blood made up of cells mainly red blood cells After centrifugation the heavier red cells settle to 1.0 the bottom of the tube plasma The straw-coloured plasma centri remains at the top fuge The two layers are 0.5 separated by a buffy coat buffy coat of white cells and platelets red cells Normal values for Ht 0 range between 0.42-0.47 blood generally larger in men than women sample
16 MEASUREMENT OF HAEMATOCRIT The haematocrit ratio (Ht) is the proportion of blood made up of cells - mainly red blood cells. blood sample centrifuge plasma buffy coat red cells 1.0 0.5 0 After centrifugation the heavier red cells settle to the bottom of the tube. The straw-coloured plasma remains at the top. The two layers are separated by a ‘buffy coat’ of white cells and platelets. Normal values for Ht range between 0.42 - 0.47, generally larger in men than women