Chapter 3 BLOOD Section 1 Composition and Properties of the blood
2 Chapter 3 BLOOD Section 1 Composition and Properties of the Blood
Blood )a suspension solution of blood cells in plasma >circulating through the cardiovascular system Erythrocyte Platelet Leukocyte
3 Blood ➢a suspension solution of blood cells in plasma ➢circulating through the cardiovascular system
Whole blood Blood plasma Proteins Albumins 54% Globulins 38% Composition Other fluids Water Fibrinogen 7% and tissues 915% All others 1% cellular Electrolytes Nutrients portion Regulatory substances (formed Other solutes I Vitamins Waste Products elements) PLASMA(weight) SOLUTES Formed elements Platelets Neutrophils 45% 150,000400,000 60-70% fluid portion White blood cells 949N 5000-10,000 (plasma) Red blood cells Lymphocytes 4. 8-5. 4 million 02025%° Monocytes 3-8% Eosinophils 2-4% ,剩 0.5-1 BODY WEIGHT VOLUME FORMED ELEMENTS LEUKOCYTES number per uL)
4 Composition ➢ cellular portion (formed elements) ➢ fluid portion (plasma)
I Plasma Straw-colored liquid consisting of water and dissolved solutes Sodium ion is the major solute of the plasma in terms of its Plasma(55%) concentration In addition to Nat, plasma → Buffy coat, composed of white blood cells contains Red blood cells and platelets 45% many other salts and ions as well as organic molecules such as metabolites, hormones, enzymes antibodies, and other proteins
5 I Plasma ➢ Straw-colored liquid consisting of water and dissolved solutes. ➢ Sodium ion is the major solute of the plasma in terms of its concentration. ➢ In addition to Na+ , plasma contains ➢ many other salts and ions, ➢ as well as organic molecules such as metabolites, hormones, enzymes, antibodies, and other proteins
Plasma proteins constitute 7-9% of the plasma Albumins(60%0-80%) Produced by the liver Provide the osmotic pressure and necessary maintain blood volume and pressure Effective Filtration Pressure -(capillary pressure interstitial osmotic pressure)-(plasma colloid osmotic pressure interstitial hydrostatic pressure) Globulins, divided into three types X Alpha and beta globulin, produced by the liver and function to transport lipids and fat soluble vitamins in the blood y Gamma globulins are antibodies produced b lymphocytes and function in immunity
6 Plasma Proteins – constitute 7-9% of the plasma ➢ Albumins (60% - 80%) ➢ Produced by the liver ➢ Provide the osmotic pressure and necessary to maintain blood volume and pressure. ➢ Effective Filtration Pressure = (capillary pressure + interstitial osmotic pressure) – (plasma colloid osmotic pressure + interstitial hydrostatic pressure) ➢ Globulins, divided into three types: ➢ Alpha and beta globulin, produced by the liver and function to transport lipids and fat soluble vitamins in the blood. ➢ Gamma globulins are antibodies produced by lymphocytes and function in immunity