19.2 The nucleosome is the subunit of all chromatin Figure 19.6 Sequences on the DNA that lie on different turns around the nucleosome A B may be close BB八NB风八DN together. Sites 80 bp apart on linear DNA are close together on nucleosome 清苇大当
Figure 19.6 Sequences on the DNA that lie on different turns around the nucleosome may be close together. 19.2 The nucleosome is the subunit of all chromatin
19.3 DNA is coiled in arrays of nucleosomes Core DNA is the 146 bp of DNA contained on a core particle. Core particle is a digestion product of the nucleosome that retains the histone octamer and has 146 bp of DNA;its structure appears similar to that of the nucleosome itself. Linker DNA is all DNA contained on a nucleosome in excess of the 146 bp core DNA. 情華大当
Core DNA is the 146 bp of DNA contained on a core particle. Core particle is a digestion product of the nucleosome that retains the histone octamer and has 146 bp of DNA; its structure appears similar to that of the nucleosome itself. Linker DNA is all DNA contained on a nucleosome in excess of the 146 bp core DNA. 19.3 DNA is coiled in arrays of nucleosomes
Length 19.3 DNA is coiled in arrays of nucleosomes 605 Figure 19.7 Micrococcal nuclease 405 digests chromatin in nuclei into a multimeric series of DNA bands that can be separated by gel 205 electrophoresis.Photograph kindly provided by Markus Noll. 清菜大当
Figure 19.7 Micrococcal nuclease digests chromatin in nuclei into a multimeric series of DNA bands that can be separated by gel electrophoresis. Photograph kindly provided by Markus Noll. 19.3 DNA is coiled in arrays of nucleosomes
Bottom Sedimentation of nucleosomes Top 19.3 DNA is coiled in 20 arrays of nucleosomes Contbl Figure 19.8 Each multimer of nucleosomes contains the appropriate number of unit 10o0 lengths of DNA.Photograph kindly provided by John Finch. 400 200 情菜大当
Figure 19.8 Each multimer of nucleosomes contains the appropriate number of unit lengths of DNA. Photograph kindly provided by John Finch. 19.3 DNA is coiled in arrays of nucleosomes
19.3 DNA is coiled in arrays of nucleosomes Base pairs 180 160 140 Figure 19.9 Micrococcal nuclease reduces the length of nucleosome monomers in discrete steps.Photograph kindly provided by Roger Kornberg Time of digestion 清苇大当
Figure 19.9 Micrococcal nuclease reduces the length of nucleosome monomers in discrete steps. Photograph kindly provided by Roger Kornberg. 19.3 DNA is coiled in arrays of nucleosomes