ISSUES RELATED TO PERFORMANCE OF BONE GRAFT SUBSTITUTE MATERIALS Incorporation of the graft into host bone(to stabilize the graft material) by bone formation on the surface of the graft material (osteoconduction). Modulus matching of the graft material to host bone to prevent stress shielding. Osteoclastic resorption of the graft(versus dissolution) may be important because osteoclasts release regulators of osteoblast function
ISSUES RELATED TO PERFORMANCE OF ISSUES RELATED TO PERFORMANCE OF BONE GRAFT SUBSTITUTE MATERIALS BONE GRAFT SUBSTITUTE MATERIALS • Incorporation of the graft into host bone (to Incorporation of the graft into host bone (to stabilize the graft material) by bone formation stabilize the graft material) by bone formation on the surface of the graft material on the surface of the graft material (osteoconduction osteoconduction). • Modulus matching of the graft material to host Modulus matching of the graft material to host bone to prevent stress shielding. bone to prevent stress shielding. • Osteoclastic Osteoclastic resorption of the graft (versus resorption of the graft (versus dissolution) may be important because dissolution) may be important because osteoclasts osteoclasts release regulators of osteoblast release regulators of osteoblast function. function
Image removed due to copyright considerations Migration of synthetic hydroxyapatite particles from the periodontal defect in which they were implanted
Image removed due to copyright considerations. Migration of synthetic hydroxyapatite particles from the periodontal defect in which they were implanted