Nitrogen- Base containing base Phosphate group Deoxyribose Sugar (a sugar) OH H Look ma, no oxygen! Deoxyribonucleotide
Base H Sugar Phosphate dAMP dTMP HN DH dGMP dCMP Deoxyribonucleotides
Nitrogen-containing base Phosphate groups (A,T,C,G in DNA,A.U,C,G in RNA) CH2 Base 0 P-O CH2 Base 0 NTP H (ribonucleoside triphosphate) OH OH dNTP H (deoxyribonucleoside OH triphosphate) 0 CH2 No oxygen 0 Base H H 0 NDP (ribonucleoside diphosphate) OH OH OP0POP一O CH2 Base 0 CH2 ddNTP Base (dideoxyribonucleoside triphosphate) H H No oxygen NMP OH OH (ribonucleoside monophosphate)
体内重要的游离核苷酸及其衍生物 ●多磷酸核苷酸：NMP,NDP,NTP ●环化核苷酸：CAMP,cGMP ·含核苷酸的生物活性物质： NAD+、NADP+、COA-SH、FAD等都含有AMP NH, NH2 NH2 .CONH2 -CONH2 0 0 HO 0 0 CH-0-P-0.P-0-CH2 H CH2-0-P-0-P-0-CH2 OH HO OH HO OHOH 0 H 夕 H OH OH ②月H NAD NADP+ 0=p-0H OH
体内重要的游离核苷酸及其衍生物 • 含核苷酸的生物活性物质： NAD+ 、NADP+ 、CoA-SH、FAD 等都含有AMP ⚫ 多磷酸核苷酸：NMP，NDP，NTP ⚫ 环化核苷酸: cAMP，cGMP N O O CH2 OH OH N N N NH2 P O OH HO AMP N O O CH2 OH OH N N N NH2 P O OH P O O OH HO ADP N O O CH2 OH OH N N N NH2 P O OH P O O OH P O O OH HO ATP N O O CH2 O OH N N N NH2 O P OH cAMP NADP+ NAD+
一-CH2 Guanine 0 OH OH Guanosine triphosphate(GTP) Guanylate cyclase PP -CH2 Guanine 0 OH Cycllc GMP (cGMP)