Chapter 5 Linkage, Recombination, and the Mapping of Genes on Chromosomes 5-1
5-1 Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Linkage, Recombination, and the Linkage, Recombination, and the Mapping of Genes on Chromosomes Mapping of Genes on Chromosomes Chapter 5
Sections to study5.1 Gene linkage and recombination5.2 The Chi-square test and linkage analysis5.3 Recombination: A result of crossing-over duringmeiosis5.4Mapping:Locatinggenes along a chromosome5.5 Tetrad analysis in fungi5.6Mitotic recombination and genetic mosaics5-2
5-2 Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display 5.1 Gene linkage and recombination 5.1 Gene linkage and recombination 5.2 The Chi 5.2 The Chi-square test and linkage analysis square test and linkage analysis 5.3 Recombination: A result of crossing 5.3 Recombination: A result of crossing -over during over during meiosis meiosis 5.4 Mapping: Locating genes along a chromosome 5.4 Mapping: Locating genes along a chromosome 5.5 Tetrad analysis in fungi 5.5 Tetrad analysis in fungi 5.6 Mitotic recombination and genetic mosaics 5.6 Mitotic recombination and genetic mosaics Sections to study Sections to study
5.1Gene linkage and recombinationHIndependentassortmentGenes on differentchromosomesGametes福B3AB: Ab: aB: ab=l: 1: 1: 15-3
5-3 Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display 5.1 Gene linkage and recombination 5.1 Gene linkage and recombination A a B b a B A B a b A b Gametes AB: Ab: aB: ab=1: 1: 1: 1 Independent assortment Independent assortment Genes on different Genes on different chromosomes chromosomes
Genetic linkageTwo genes on the same chromosome segregate together.mm9GametesAB: Ab:aB: ab=2:0:0:25-4
5-4 Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Genetic linkage Genetic linkage Two genes on the same chromosome segregate together. Two genes on the same chromosome segregate together. A a B b Gametes a b A B A B a b AB: Ab: aB: ab=2: 0: 0: 2
w and y genes are X-linked in DrosophilaPQwwyyt xowty/y+w+wyty × owy+/ymales-4484W yt /YThomas H.MorganParentaltypes:4413wt y/Y4484+4413× 100=99%wt: brick-red eyes9026w: white eyes76wt y+ /Yy+: brown bodyRecombinanttypes:53wy/yy: yellow body76+53×100=1%Total 90269026Y:Y chromosomeFig.5.25-5
5-5 Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display Fig. 5.2 w +: brick-red eyes w: white eyes y +: brown body y: yellow body Y: Y chromosome w and y genes are X-linked in Drosophila Thomas H. Morgan