苏州大学医学部 教 案 课程名称： Biochemistry V 授课对象： 2019级药学 授课学时： 54 教材版本： 生物化学与分子生物学（第9版），人民 卫生出版社 主讲教师： 刘晶晶高媛/张艳岭/苏雄/程坚/赵昀 苏州大学基础医学与生物科学学院制 2020年08月20日
苏州大学医学部 教 案 课程名称： Biochemistry V 授课对象： 2019 级药学 授课学时： 54 教材版本： 生物化学与分子生物学(第 9 版)，人民 卫生出版社 主讲教师： 刘晶晶/高媛/张艳岭/苏雄/程坚/赵昀 苏州大学基础医学与生物科学学院制 2020 年 08 月 20 日
Teaching plan of Soochow University Subjects:BIOCHEMISTRY Class:2019 Pharmaceutical Sciences Date:2020.9.9/Wed/5-6 Teaching duration:100 Chapter Text page:2-29 min Title Physical-Chemical Foundations of Biochemistry Teaching Foundations of Biochemistry goal Teaching content、 1.Biological Foundations 50 min 1.1 Classification System of Life 15 Teaching 1.2 Molecular Evolution 20 method、 1.3 Prokaryotes and Eukaryotes 15 Teaching 2.Chemical Foundations 50 min emphasis、 2.1 Elements in Life 5min difficulty、 2.2 Conformation vs Configuration 25min 2.3 Thermodynamics of Life 20min time distribution Teaching Multimedia teaching combine with PPT and viedo instrument Question 1. Chemistry Jargons in Biochemistry and quiz in class After class Prokaryotes and Eukaryotes summary Conformation and Configuration
Teaching plan of Soochow University Subjects：BIOCHEMISTRY Class：2019 Pharmaceutical Sciences Date：2020. 9. 9／Wed／5-6 Chapter 1 Text page：2-29 Teaching duration:100 min Title Physical-Chemical Foundations of Biochemistry Teaching goal Foundations of Biochemistry Teaching content、 Teaching method、 Teaching emphasis、 difficulty、 time distribution 1.Biological Foundations 50 min 1.1 Classification System of Life 15 1.2 Molecular Evolution 20 1.3 Prokaryotes and Eukaryotes 15 2.Chemical Foundations 50 min 2.1 Elements in Life 5min 2.2 Conformation vs Configuration 25min 2.3 Thermodynamics of Life 20min Teaching instrument Multimedia teaching combine with PPT and viedo Question and quiz in class 1. Chemistry Jargons in Biochemistry After class summary • Prokaryotes and Eukaryotes • Conformation and Configuration
Teaching plan of Soochow University Subjects:BIOCHEMISTRY Class:2019 Pharmaceutical Sciences Date:2020.9.9/Wed/7 Chapter 3 Text page:71-100 Teaching duration:50 Title Proteins Teaching Amino Acid Composition and linkage in Proteins goal Teaching content、 1.Molecular Composition of Proteins (50 min) Teaching 1.1 Proteins perform a variety of dynamic and structural functions 15 nethod、 1.2 All amino acids in proteins are L steroisomers 20 Teaching 1.2.1 Amino acid are zwitterions emphasis、 1.2.2 Amino acid side chains form many noncovalent interaction difficulty、 1.3 Peptide bonds and disulfide bonds form the primary structure of proteins 15 time distribution Teaching Multimedia teaching combine with PPT and viedo instrument Question 1.Molecular structure of proteins and quiz in class Proteins consist of 20 amino acids,held together by peptide bonds.The covalent structure of a protein is called its primary structure.The covalent After class structure of a protein is called its primary structure. summary 。 Secondary structure is the local spatial arrangement of a polypeptide's backbone atoms
Teaching plan of Soochow University Subjects：BIOCHEMISTRY Class：2019 Pharmaceutical Sciences Date：2020. 9. 9／Wed／7 Chapter 3 Text page：71-100 Teaching duration: 50 Title Proteins Teaching goal Amino Acid Composition and linkage in Proteins Teaching content、 Teaching method、 Teaching emphasis、 difficulty、 time distribution 1.Molecular Composition of Proteins （50 min） 1.1 Proteins perform a variety of dynamic and structural functions 15 1.2 All amino acids in proteins are L steroisomers 20 1.2.1 Amino acid are zwitterions 1.2.2 Amino acid side chains form many noncovalent interaction 1.3 Peptide bonds and disulfide bonds form the primary structure of proteins 15 Teaching instrument Multimedia teaching combine with PPT and viedo Question and quiz in class 1. Molecular structure of proteins After class summary • Proteins consist of 20 amino acids, held together by peptide bonds. The covalent structure of a protein is called its primary structure. The covalent structure of a protein is called its primary structure. • Secondary structure is the local spatial arrangement of a polypeptide’s backbone atoms
Teaching plan of Soochow University Subjects:BIOCHEMISTRY Class:2019 Pharmaceutical Sciences Date:2020.9.16/Wed/5-7 Teaching duration: Chapter 4 Text page:100-152 150min Title Proteins Molecular Structure of proteins (The Teaching primary structure of proteins. three-dimensional of proteins) goal 2.Protein structure (50 min) 2.IThe sequence of amino acids is the primary structure of proteins 20 2.2The secondary structure has regularly repetitive folding patterns of polypeptides 30 2.2.1 the a-helix and B-pleated sheet are the most common secondary structure in Teaching proteins content、 2.2.2 B-turn makes a tight 180-degree turn Teaching 2.Protein structure (50min) nethod、 2.3 Tertiary structure of proteins 40 2.3.1 Tertiary structure is the three-dimensional structure of an entire polypepide Teaching 2.3.2 Noncovalent interaction stabilize protein conformation emphasis、 2.3.3 Chaperone proteins assist in the correct folding of proteins difficulty、 2.4 Quaternary structure of proteins 10 time 3.Protein structure and function of protein (50min) distribution 3.1 Relationships of primary structure and function 25 3.2 Structure-function relationships of myoglobin and hemoglobin 5 3.4 Oxygen binding to hemoglobin is cooperative 15 3.5 2,3-bisphosphoglycerate is a negative allosteric effector of oxygen Binding to hemoglobin Multimedia teaching combine with PPT and viedo Question and quiz in Structure-function relationships of protein class
Teaching plan of Soochow University Subjects：BIOCHEMISTRY Class：2019 Pharmaceutical Sciences Date：2020.9.16／Wed／5-7 Chapter 4 Text page：100-152 Teaching duration: 150min Title Proteins Teaching goal Molecular Structure of proteins (The primary structure of proteins, three-dimensional of proteins) Teaching content、 Teaching method、 Teaching emphasis、 difficulty、 time distribution 2.Protein structure （50 min） 2.1The sequence of amino acids is the primary structure of proteins 20 2.2The secondary structure has regularly repetitive folding patterns of polypeptides 30 2.2.1 the α-helix and β-pleated sheet are the most common secondary structure in proteins 2.2.2 β-turn makes a tight 180-degree turn 2.Protein structure （50min） 2.3 Tertiary structure of proteins 40 2.3.1 Tertiary structure is the three-dimensional structure of an entire polypepide 2.3.2 Noncovalent interaction stabilize protein conformation 2.3.3 Chaperone proteins assist in the correct folding of proteins 2.4 Quaternary structure of proteins 10 3. Protein structure and function of protein （50min） 3.1 Relationships of primary structure and function 25 3.2 Structure-function relationships of myoglobin and hemoglobin 5 3.4 Oxygen binding to hemoglobin is cooperative 15 3.5 2,3-bisphosphoglycerate is a negative allosteric effector of oxygen Binding to hemoglobin 5 Multimedia teaching combine with PPT and viedo Question and quiz in class Structure-function relationships of protein
The relationship between structure and function of protein is most difficult for students to understand. After class Tertiary structure refers to the three-dimensional structure of a polypeptide summary Quaternary structures are defined by the interactions between different subunits
After class summary The relationship between structure and function of protein is most difficult for students to understand. • Tertiary structure refers to the three-dimensional structure of a polypeptide. • Quaternary structures are defined by the interactions between different subunits. •