Orthomyxovirus and Paramyxovirus Influenza, Corona SaRs, avian flu and other respiratory viruses Chao ZHAo(赵超) MOH&MOE Key Lab of Medical Molecular Virology Shanghai Medical College, Fudan University 复旦大学上海医学院分子病毒学教育部/卫生部重点实验室 Nov15,2013
Orthomyxovirus Orthomyxovirus and Paramyxovirus Paramyxovirus I fl C SARS i fl d h Influenza, Corona SARS, avian flu and other respiratory viruses Chao ZHAO(赵 超) MOH&MOE Key Lab of Medical Molecular Virology Shanghai Medical College Shanghai Medical College, Fudan University University 复旦大学上海医学院分子病毒学教育部/卫生部重点实验室 Nov 15, 2013
TOPIC: what is the biggest challenge ·War? Food safet Finance crisis Natural disasters, eg earthquake acute infectious diseases, esp respiratory viruses infection (RvD) Chronic disease aging Biosafety bioterror(ism)
TOPIC: what is the biggest challenge • War? • Food safet y • Finance crisis Finance crisis • Natural disasters, eg earthquake… • acut i f ti di i t te i n fectious diseases, esp resp ira tory viruses infection (RVI) • Chronic disease & a gin g • Biosafety & Bioterror(ism) Biosafety & Bioterror(ism)
Why is Rvi Easy transmit · large population Worldwide(wide geographic spread) Emergency Variant/mutant
Why is RVI • Easy transmit • large population • Worldwide ( Worldwide (Wide geographic spread Wide geographic spread) • Emergency • Variant/mutant
EXAMPLE:1918 Influenza Pandemic
EXAMPLE:1918 Influenza Pandemic
1918 Influenza Pandemic Caused 40 milion deaths worldwide Mainly the young 80% of Us Army deaths in World War I resulted from infection with influenza virus We still do not understand fully why this strain of influenza a virus was so devastating to the younger population
1918 Influenza Pandemic 1918 Influenza Pandemic • C d 40 illi d th ld id Cause d 40 million deaths world wid e – Mainly the young! • 80% of US Army deaths in World War I result d f i f ti ith i fl lt e d from in fection with influenza virus • We still do not understand fully why this st i f I fl A i train o f Influenza A virus was so devastating to the younger population