Arthropod-borne viruses(Arboviruses) rodent-borne viruses (虫媒病毒&病毒性出血热) Shibo Jiang(姜世勃) MOH&MOE Key Lab of Medical Molecular Virology Shanghai Medical College, Fudan University 复旦大学上海医学院分子病毒学教育部/卫生部重点实
Arthropod-borne viruses (Arboviruses) & rodent-borne viruses (虫媒病毒 & 病毒性出血热) Shibo Jiang (姜世勃) MOH&MOE Key Lab of Medical Molecular Virology Shanghai Medical College, Fudan University 复旦大学上海医学院分子病毒学教育部/卫生部重点实验室
Comparison of arthropod- and rodent-borne viruses Viruses arthropod-borne viruses rodent-borne viruses Reservoir hosts arthropods(e.g, mosquitoes, and rodents (e.g, mice, rats, ticks) squirrels, and hamsters) bloodsucking arthropods from one contact with body fluids or Transmitted by vertebrate host to another excretions of rodents ellow fever, dengue, Japanese b hantavirus infections encephalitis, St Louis encephalitis, Lassa fever, South Major diseases western equine encephalitis, eastern American hemorrhagic equine encephalitis, Russian spring- fevers, and African summer encephalitis, West Nile hemorrhagic fevers fever, and sandfly fever (Marburg and Ebola
Viruses arthropod-borne viruses rodent-borne viruses Reservoir hosts arthropods (e.g., mosquitoes, and ticks) rodents (e.g., mice, rats, squirrels, and hamsters) Transmitted by bloodsucking arthropods from one vertebrate host to another contact with body fluids or excretions of rodents Major diseases yellow fever, dengue, Japanese B encephalitis, St. Louis encephalitis, western equine encephalitis, eastern equine encephalitis, Russian springsummer encephalitis, West Nile fever, and sandfly fever hantavirus infections, Lassa fever, South American hemorrhagic fevers, and African hemorrhagic fevers (Marburg and Ebola) Comparison of arthropod- and rodent-borne viruses
Part Arthropod-borne viruses (Arboviruses Overview General information of arbovirus Main properties of togaviruses (alphavirus) Chikungunya caused by alphavirus Main properties of flaviviruses Dengue fever caused by flavivirus Japanese B Encephalitis caused by flavivirus
Part I Arthropod-borne viruses (Arboviruses ) Overview General information of arbovirus Main properties of togaviruses (alphavirus) Chikungunya caused by alphavirus Main properties of flaviviruses Dengue fever caused by flavivirus Japanese B Encephalitis caused by flavivirus
Arboviruses Arboviruses spread by arthropod vectors such as mosquitoes, ticks, and flies It has four families: togaviruses, flaviviruses bunyaviruses and reoviruses The major arbovirus disease worldwide are yellow fever, dengue, Japanese B encephalitis, St Louis encephalitis, Russian spring-summer encephalitis Most illnesses caused by these viruses are mild fevers; some may cause severe encephalitis, and life-threatening hemorrhagic fever
Arboviruses spread by arthropod vectors, such as mosquitoes, ticks, and flies It has four families: togaviruses, flaviviruses, bunyaviruses and reoviruses The major arbovirus disease worldwide are yellow fever, dengue, Japanese B encephalitis, St. Louis encephalitis, Russian spring-summer encephalitis. Most illnesses caused by these viruses are mild fevers; some may cause severe encephalitis, and life-threatening hemorrhagic fever. Arboviruses
The influence of the vectors Vectors and viruses tend to be clustered in the tropics and subtropics; many temperate zones have periodic epidemics Arbovirus life cycles are closely tied to the ecology of the vectors Infections show a peak incidence when the arthropod is actively feeding and reproducing(e. g Dengue fever's peak in Taiwan is Oct or Nov) Humans can serve as dead-end. accidental hosts or a maintenance reservoir Controlling the vector controls the disease
The influence of the Vectors Vectors and viruses tend to be clustered in the tropics and subtropics; many temperate zones have periodic epidemics. Arbovirus life cycles are closely tied to the ecology of the vectors. Infections show a peak incidence when the arthropod is actively feeding and reproducing (e.g., Dengue fever’s peak in Taiwan is Oct or Nov). Humans can serve as dead-end, accidental hosts or a maintenance reservoir. Controlling the vector controls the disease