上帝充通大学 Shanghai Jiao Tong University 5.12.1 Molecular basis for growing at extreme temperatures 1.Molecular adaptations of enzymes to extreme temperatures Cold-active enzymes are more flexible due to higher portion of o helix and less amount of B-sheeti耐冷的酶因 为有更高比例的o螺旋而更具弹性 Heat resistant enzymes more salt bridges and more densely packed hydrophobic interior抗热的酶与嗜温菌 的酶比较，在特定的重要位点有不同的氨基酸，有更多 的盐键和更多紧密的疏水内部区域 No.16 Shanghai Jiao Tong University
No.16 Shanghai Jiao Tong University 5.12.1 Molecular basis for growing at extreme temperatures 1. Molecular adaptations of enzymes to extreme temperatures • Cold-active enzymes are more flexible due to higher portion of a helix and less amount of b-sheet耐冷的酶因 为有更高比例的a螺旋而更具弹性. • Heat resistant enzymes : more salt bridges and more densely packed hydrophobic interior 抗热的酶与嗜温菌 的酶比较,在特定的重要位点有不同的氨基酸,有更多 的盐键和更多紧密的疏水内部区域
More a-helixes result in more flexible structure,which is cold resistant Key 八人 a.-Helix Achain B-Sheet Disulfide bond B chain
More a-helixes result in more flexible structure, which is cold resistant