上游充通大 SHANGHAI JIAO TONG UNIVERSITY Antibacterial spectrum Antibacterial spectrum: Gram-positive cocci Staphylococcus infections Gram-negative cocci:Staphylococcus pneumoniae infection Gram-positive bacilli:diphtheria(白喉)， tetanus(破伤风) Leptospira (螺旋体)：leptospirosis(钩端螺 旋体病) Actinomycetes (放线菌)：actinomycosis (放线菌病)
Antibacterial spectrum Antibacterial spectrum: ü Gram-positive cocci : Staphylococcus infections ü Gram-negative cocci: Staphylococcus pneumoniae infection ü Gram-positive bacilli: diphtheria（白喉）， tetanus（破伤风） ü Leptospira（螺旋体）: leptospirosis（钩端螺 旋体病） ü Actinomycetes（放线菌）：actinomycosis （放线菌病）
上泽充通大学 SHANGHAI JIAO TONG UNIVERSITY Neisseria gonorrhoeae 淋病奈瑟菌
淋病奈瑟菌
上泽充通大学 SHANGHAI JIAO TONG UNIVERSITY 放线菌
放线菌
上泽充通大学 SHANGHAI JIAO TONG UNIVERSITY 放线菌病
放线菌病
上游充通大 Mechanism of penicillin SHANGHAI JIAO TONG UNIVERSITY B-Lactam antibiotics work by binding to transpeptidase and then inhibiting the formation of peptidoglycan cross- links in the bacterial cell wall
Mechanism of penicillin β-Lactam antibiotics work by binding to transpeptidase and then inhibiting the formation of peptidoglycan crosslinks in the bacterial cell wall