Lipidemic modulating drugs Antiatherosclerotic agents Abnormal blood flow Plaque Narrowing of artery Narrowed Plaque artery
Lipidemic modulating drugs Antiatherosclerotic agents
Causes High blood cholesterol ■High blood pressure o Smoking o( Obesity Lack of physical activity
High blood cholesterol High blood cholesterol High blood pressure High blood pressure Smoking Smoking Obesity Obesity Lack of physical activity Lack of physical activity
section 1 introduction 1.atherosclerosis 2.the composition of blood lipid 口cholesteryl esters(CE,胆固醇酯) ▣triglycerides(TG,甘油三酯)， ▣cholesterol,.(Ch胆固醇 ▣phospholipids (PL磷脂) 口apolipoproteins(载脂蛋白)
section 1 introduction 1.atherosclerosis 1.atherosclerosis 2.the composition of blood lipid 2.the composition of blood lipid cholesteryl cholesteryl esters(CE esters(CE, 胆固醇酯 ) triglycerides (TG triglycerides (TG，甘油三酯), cholesterol, (Ch cholesterol, (Ch 胆固醇 ) phospholipids (PL phospholipids (PL磷脂） apolipoproteins apolipoproteins（载脂蛋白）
3.major lipoprotein classes: *chylomicron VLDL IDL LDL HDL 4.the action of lipoprotein in atherosclerosis formation VLDL,LDL,IDL,apoB HDL,apoA
3. major lipoprotein classes: 3. major lipoprotein classes: chylomicron chylomicron VLDL IDL LDL HDL VLDL IDL LDL HDL 4. the action of lipoprotein in atherosclerosis 4. the action of lipoprotein in atherosclerosis formation formation VLDL, LDL, IDL, VLDL, LDL, IDL, apoB HDL, apoA
4.forms of hyperlipoproteinemia form ipoprotein abnormality plasma lipid abnormality CM t TG TC LDL Tc Ib VLDL,LDL TGTC m IDL TGTC VLDL TG CM,VLDL
4. forms of hyperlipoproteinemia form ipoprotein ipoprotein abnormality abnormality plasma lipid abnormality plasma lipid abnormality I CM TG TC TG TC IIa LDL TC IIb VLDL, LDL VLDL, LDL TG TC TG TC III IDL TG TC TG TC IV VLDL TG V CM, VLDL CM, VLDL TG TC TG TC