PathologY
PathologyMaculopapule· Angiotelectasis indermis.Vesicles. Ballooning degeneration incelllayer.Cloudyvesicless.Apocyteinvadeherpes.herpes fluidabsorbedCrust. Absence ofbrownish discolorationdecrustation
Pathology • Maculopapule • Vesicles • Cloudy vesicles • Cru st • d ecru sta tion • Angiotelectasis in dermis • Ballooning degeneration in celllayer • Apocyte invade h erp es • h erp es fluid a b sorb ed • Ab s en ce of b rown is h d is colora tion
Clinical manifestations
Clinical ManifestationsThe severity ofthe disease varies from a few lesionswith little evidence of systemic illness to manyhundreds oflesions and extremetoxicity Incubation period:theincubation period varies from 1 -21 days but is13-17days inthemajority of instances.Typical varicella: prodromal period: 24 hrthere may be slightfever, malaise,or anorexia
Clinical Manifestations The severity of the d isea se varies from a few lesions with little evidence of systemic illness to many h u n d red s of lesions a n d extreme toxicity • Incubation period: the incubation period varies from 1 -21 d a ys but is 13- 17 d a ys in the majority of instances. Typical varicella • prodromal period: 24 hr there may b e slight fever, malaise ,or anorexia
Clinical Manifestations. Exanthem stage:rash development process:maculopapule-- “tear-drop"vesicles--cloudy vesicles--crustsrash characteristic:stage by stageappearthree species rash at the same timecentrality spreadmucosa involvementrash sequence:trunk-- face and scalp--extremities
• Exanthem stage: r ash development p r ocess: maculopapule - “tear-drop” vesicles-cloudy vesicles-crusts r ash characteristic: s ta ge by sta ge a p p ea r th ree s p ecies ra s h a t th e s ame time centrality sp rea d mu cos a involvement r ash seq uence: trunk- face a n d scalp- -extremities Clinical Manifestations