Chapter 1o Adrenoceptor Antagonist DrugsThe classification of the adrenoceptor antagonist drugsα-AdrenoceptorAntagonistDrugs(Phentolaminephenoxybenzamineβ-AdrenoceptorAntagonistDrugs(Propranolol,timolol,metoprolol)
The classification of the adrenoceptor antagonist drugs -Adrenoceptor Antagonist Drugs (Phentolamine phenoxybenzamine ) β-Adrenoceptor Antagonist Drugs (Propranolol , timolol, metoprolol) Chapter 10 Adrenoceptor Antagonist Drugs
I.Basic pharmacology of the α antagonist drugsMechanismOfActiona-adrenoceptor blocking drugs can selectivelycombine with a-receptor,block the receptors andantagonize the effects of a-agonists.Adrenoceptorblocking drugs may be reversible (Phentolaminetolazoline)orirreversible (phenoxybenzamine,dibenamine)in their interaction with these receptors
Mechanism Of Action α-adrenoceptor blocking drugs can selectively combine with α-receptor, block the receptors and antagonize the effects of α-agonists. Adrenoceptor blocking drugs may be reversible ( Phentolamine, tolazoline) or irreversible (phenoxybenzamine, dibenamine) in their interaction with these receptors. I.Basic pharmacology of the antagonist drugs