Gene expressionDNATemplatestrandTranscriptionCmRNA1CodonTranslationProteinMetProLeuAlaArgTaminoacidchain)MethionineProlineLeucineAlanineArginine
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY
Second letterGUCAUUUUUAUUGUPhenyl-UCUTyrosineCysteineUUCUACCUGCUCCalanineUSerineUCAAUGAUUAUAAStopcodonStop.codonLeucineUCGUAGUUGGUGGStopcodonTryptophanUCAUCGUCUUCCUHistidineCACCCCCCGCCUCProlineLeucineArginineCGACCACUAACAAGlutamineCGGCUGCCGCAGGUAAUAGUAUUACUSerineAsparagineAGCAUCAACIsoleucineCACC-ThreonineAUAACAMethionineAAAAAGALysineArginineACGinitiationAUGAAGAGGGcodonUGAUGUUGCUAsparticGGUGACCGCCGGCGUCacidGValineAlanineGlycineGUAGCAGGAAGAAGlutamicGUGGCGGGGGAGGacid
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY
CAU启HHMetHHGAUStart CodonGGAOGGCUGCCCCUCCOU剪mmnC35
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY
AUGlyPheGluHHHHSerHHAAStopCodonAAN(also UAG and UGA)UCCCCCOLCUU35
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY
mRNA----Template for protein synthesisCharacteristics of codon:>Commaless:The genetic code is nonoverlapping and commaless- that is,the code is read from a fixed starting point as a continuoussequence of bases, taken three at a time.>Degeneracy(Redundancy):(1) Besides Trp （W) and Met （M) ， The other aminoacids have more than one triplet genetic codon.(2) It usually change on the third of nucleotide in thenucleotide -codonDepartment of Biochemistry and Molecular Biology,MedicineSchool
Department of Biochemistry and Molecular Biology, Medicine School BIOCHEMISTRY AND MOLECULAR BIOLOGY Characteristics of codon： ➢Commaless: The genetic code is nonoverlapping and commaless- that is, the code is read from a fixed starting point as a continuous sequence of bases, taken three at a time. ➢Degeneracy(Redundancy): (1) Besides Trp（W) and Met（M），The other amino acids have more than one triplet genetic codon. (2) It usually change on the third of nucleotide in the nucleotide codon mRNA-Template for protein synthesis