Adaptive Immune Responses Feature I Functional significance Specificity E sures that distinct antigens elicit specific responses Diversity Enables immune system to respond to a large variety of antigens Memory Leads to enhanced responses to repeated exposures to the same antigens Specialization Generates responses that are optimal for defense against different types of microbes Self-limitation Allows immune system to respond to newly encountered antigens Nonreactivity Prevents injury to the host during to self responses to foreign antigens
Adaptive Immune Responses
Adaptive Immune Responses Cellular Components Lymphocytes B, Th CTL nKt Antigen-presenting cells(APCs) DC Mo, B Effector cells Activated T cells, mononuclear phagocytes
Cellular Components Adaptive Immune Responses • Lymphocytes - B, Th, CTL, NKT • Antigen-presenting cells(APCs) - DC, Mj, B • Effector cells - Activated T cells, mononuclear phagocytes
Basic Immunology Recognition Activation Effection Ag(antigen) double recognition humural immunity APC double signaling cellular immunity (antigen presenting cell)
Basic Immunology Recognition Activation Effection Ag (antigen) double recognition humural immunity APC double signaling cellular immunity (antigen presenting cell)
Chapter 1 efinition ofantigen Antigen(Ag) Substances that combine specifically with a B or T cell's antigen-binding receptors can then induce an immune response are called antigens
Antigen (Ag) Chapter 1 Definition of antigen Substances that combine specifically with a B or T cell’s antigen-binding receptors can then induce an immune response are called antigens
Chapter 2 Characteristics ofantigen The antigen molecule generally pose two natures, that is (1) immunogenicity (2) antigenicity
Chapter 2 Characteristics of antigen （1）immunogenicity （2）antigenicity The antigen molecule generally pose two natures, that is