刘新文,蛋白质生物合成 解读密码 Table 26-3 Polypeptide produced in response to synt c RNA polymers with repeating sequences of three and four base Polynucleotide Polypeptide products Trinucleotide repeats (UUC). (Phe), (Ser). (Leu), (AAG) (LyB). (Arg).(Glu (UUG) (Leu). (Cys). (Val), (CCA) (Pro), (His), (Thr (GUA). /). (Ser).(chain terminator) (UAC. (Tyr). (Thr). (eu). (AUC). (e), (Ser). (His]. (GAU) (Asp). (Met).(chain terminator). Tetranucleotide repeats (UAUC). (Tyr-Leu-Ser-Dle) (UUACh L Thr-Tyrh. (GUAAl. Di and tripeptides (AUAG). Di- and tripeptides
刘新文，蛋白质生物合成
Second letter of codon G UUU Phe: UC Ser UAU Tyr UGU Cy UUC Phe UCC Ser UAC Tyr UGC Cy U 如器關 First CU co Pro CAA GlnCGA Arg letter of CUG CCG Pro CAG Gin CGG codon (6’end AUU De ACU Thr AAU AanAGU AUC ne ACC Thr AAC AanAGC Ser AUA ne ACA AGA ArK MetACG 删始如 AGG ArK GUU Val GCU GAU GGU GI GUC Val GCC AlaGAC GGC Gly G GUA Val GcA Ala GAA GluGGA GUG Val GCG AIn GAG Glu GGG Gly
刘新文，蛋白质生物合成
刘新文,蛋白质生物合成 1、密码子不重叠 Nonoverlapping A U AC G AG CL Overlapp AUACGAGU C 1 3 2、密码子的连续性与方向性 Reading frame15--日0UΔΔ G UA A GU AAG U AA G UA A---3 Reading frame 2 GAAB雙在医AA Reading frame3-GUAA@Dλ^@ UAA G UA A圓AA-一
刘新文，蛋白质生物合成 1、密码子不重叠 2、密码子的连续性与方向性
刘新文,蚕白质生物合成 Table 26- Degeneracy of the genetic cod Amino Number of A mIno Number of d codons cid COONe Ala Lys Met 621 码简并 Gin 4622222 mmw 性 Glu Gly His TT 246412+ 3 Val
刘新文，蛋白质生物合成
刘新文,蛋白质生物合成 Wobble positions in Anticodon and codon Interactions c A GCU UAG CUA Wobble positions in codon and Anticodon Interactions c A GCU UAG 密码配对的摇摆性 Anticodon (3)GC-1 G Codon °)
刘新文，蛋白质生物合成 4、 密 码 配 对 的 摇 摆 性