Compact chromatin RNA polymerase H (H3H4)2H2AH2B hexamer H3 er H4 H4 H2B H3 H2A RNA polymerase
Form II B FormⅢ C
parental strand TTGGGGTTGGGGTTGGGGTT AACCCC 5 incomplete, newly synthesized lagging strand TELOMERASE BINDS TTGGGGTTGGGGTTGGGGTTG telomerase AACCCC CCCCAACI TELOMERASE EXTENDS 3 END (RNA-templated telomerase with bound RNA template DNA synthesis) TTGGGGTTGGGGTTGGGGTTGGGGTTGGGGTT AACCCC CCCCAAC COMPLETION OF LAGGING STRAND BY DNA POLYMERASE DNA-templated DNA synthesis) TTGGGGTTGGGGTTGGGGTTGGGGTTGGGGTTG AACCCC CCCCAACCCCAACCCC DNA polymerase
Template strand Coding strand ATGCGCCATGCCAGTTACGTACATGGA TACGCGGTACGGTCAATGCATCTACCT RNA sequence is TRANSCRIPTION complementary to template strand identical to coding strand UACGCGGUACGGUCAAUGCAUCUACCU RNA transcript
nation Only one reading frame is open Termination Third reading frame is blocked Termination