CH2OH CH2OH CH>OH CH2OH HP OH OH OH HO -OR OH OH Glycogen Glucose 1-phosphate Glycogen (n residues) (n-1 residues)
CH2OH -0 HO OH CH>OH H,0 OH OH OH o1,6-Gluco- sidase RO OH HO OH OH HO OR OH Glycogen Glucose Glycogen (n residues) (n-I residues)
Phosphoglucomutase Converts Glucose 1-phosphate into Glucose 6-phosphate Liver Contains Glucose 6-phosphatase,a Hydrolytic Enzyme Absent from Muscle Glucose 6-phosphate +H2O->glucose Pi
⚫ Phosphoglucomutase Converts Glucose 1-phosphate into Glucose 6-phosphate ⚫ Liver Contains Glucose 6-phosphatase, a Hydrolytic Enzyme Absent from Muscle
转移酶 Limit branch(4 glucose residues) Glycogen debranching enzyme This a-1,6 bond will be hydrolyzed by the debranching enzyme also These a-1,4 bonds are now available for hydrolysis by phosphorylase
转移酶
a1→4) a16) ()②③®9○o②C③@0X3D0 Glycogen chain after action of phosphorylase Debranching enzyme transferase activity Q- OOcxo (b)@②③②@0X●○©OO@ H2O- Debranching enzyme a(1-6)-glucosidase OH activity (c)©3@②0○@⑧0○●②@D Glycogen chain ready for continued action of phosphorylase