第十二章脂类代谢 Apolipoproteins Cholesterol Phospholipids Triacylglycerols and cholesteryl esters
第十二章脂类代谢
モ)テ（丰口）20日AFP=時事】最高時二仗体重 560卡口左記録上牛口)又又工儿.之)心è人(41) 、卡木入記録I仁登録老九石二上力分一大上。ま上之少心 è人：、200牛口の减量左達成上人上儿℃半ネ入記録 仁登绿è九石上L1。 )ベ心è人仗AFP通信I仁、「半ネ又記録I仁最老太∽大人 上L℃登録老九℃九儿。ま大、200牛口体重左减6世 ℃幸世」上語上。半ネ入記録仗)ペ心è人u左最花体重 重L八人L℃認定、2008年版少心èu)写真苍 載世、治療①過程松紹介寸石
モンテレイ（メキシコ）20日AFP＝時事】最高時には体重 560キロを記録したメキシコのマヌエル・ウリベさん（41） が、ギネス記録に登録されることが分かった。またウリベ さんは、200キロの減量を達成した人としてもギネス記録 に登録されるという。 ウリベさんはAFP通信に、「ギネス記録に最も太った人 として登録されてうれしい。また、200キロも体重を減らせ て幸せだ」と語った。ギネス記録はウリベさんを最も体重 が重い人として認定し、2008年版でウリベさんの写真を 載せ、治療の過程なども紹介する
Key Terms triacylglycerol(neutral fat, triacylglyceride) ·bile salt chylomicron acyl adenylate carnitine ·b-oxidation pathway vitamin B12(cobalamin) ·peroxisome ·ketone body acyl carrier protein (ACP) ·fatty acid synthase ·malonyl CoA acetyl CoA carboxylase
Key Terms • triacylglycerol (neutral fat, triacylglyceride) • bile salt • chylomicron • acyl adenylate • carnitine • b-oxidation pathway • vitamin B12 (cobalamin) • peroxisome • ketone body • acyl carrier protein (ACP) • fatty acid synthase • malonyl CoA • acetyl CoA carboxylase
·megasynthase ·polyketide nonribosomal peptide AMP-dependent protein kinase (AMPK) protein phosphatase 2A ·arachidonate 。prostaglandin ·eicosanoid 。l.Transducing
• megasynthase • polyketide • nonribosomal peptide • AMP-dependent protein kinase (AMPK) • protein phosphatase 2A • arachidonate • prostaglandin • eicosanoid • II. Transducing
An Overview of Fatty Acid Metabolism Fatty acid degradation and synthesis are relatively simple processes that are essentially the reverse of each other.The process of degradation converts an aliphatic compound into a set of activated acetyl units (acetyl CoA) that can be processed by the citric acid cycle (Figure 22.2).An activated fatty acid is oxidized to introduce a double bond;the double bond is hydrated to introduce an oxygen;the alcohol is oxidized to a ketone;and, finally,the four carbon fragment is cleaved by coenzyme A to yield acetyl CoA and a fatty acid chain two carbons shorter.If the fatty acid has an even number of carbon atoms and is saturated,the process is simply repeated until the fatty acid is completely converted into acetyl CoA units
An Overview of Fatty Acid Metabolism • Fatty acid degradation and synthesis are relatively simple processes that are essentially the reverse of each other. The process of degradation converts an aliphatic compound into a set of activated acetyl units (acetyl CoA) that can be processed by the citric acid cycle (Figure 22.2). An activated fatty acid is oxidized to introduce a double bond; the double bond is hydrated to introduce an oxygen; the alcohol is oxidized to a ketone; and, finally, the four carbon fragment is cleaved by coenzyme A to yield acetyl CoA and a fatty acid chain two carbons shorter. If the fatty acid has an even number of carbon atoms and is saturated, the process is simply repeated until the fatty acid is completely converted into acetyl CoA units