Goldman-Hodgkin-Katz equation RT PKKtl+pna[Na l+pccl I F PKK+pna[Na]+pci[cl]
Goldman-Hodgkin-Katz equation i o o o K K P [ ] P [Na ] P [Cl ] P [ ] P [Na ] P [Cl ] ln F RT V C l i K Na i K Na C l m + + − + + − + + + + =
Experiments Data 20 EXP 100 20 EK=59.51 160 o(mmo/
Experiments Data
Active Ion Pumping NaK-ATPase Pump is electrogenic K equilibrium potential
Active Ion Pumping • Na+ , K+ -ATPase • Pump is electrogenic • K + equilibrium potential
HH方程 I=C+(V-Vk)g n+(V-VNagNa mh+(V-V1gL at n (1-n)-Bn dt am m m dt (1-h)-Bh
H-H 方程 (1 h) h dt dh (1 m) m dt dm (1 n) n dt dn (V V )g n (V V )g m h (V V )g t V I C h h m m n n L L 3 N a N a 4 k k = − − = − − = − − + − + − + − =
Organization of Nerve System Interaction of the Sensory, Motor, and Motivational systems is essential for Even Simple behavior
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