Regulation of cell division by growth factors Growth factors cytokines MAPK cascade Phosphorylation of Jun and Fos in nucleus Transcriptional regulation C yells, ranscription CDKS factor E2F Transcriptional regulation Enzymes for DNA synthesis Passage e from GI to S ph
Regulation of cell division by growth factors
Checkpoint controls through the cell cycle Improper spindle formation (M arrest) Prophase Anaphase High Low MPF anaphase inhibitor Cell cycle DNA damage (G, arrest START DNA damage Unreplicated DNA (G, arrest (S arrest) s phase
Checkpoint controls through the cell cycle