DiagnosisHysteroscopywith endometrial curettageor endometrial sampling,curettage aloneor outpatient endometrial sampling aloneessentialCurettageeisnotareinfallible. On the other hand, if a Pipellehas been correctly introduced (record howmany cm) and the pathology is benign, or notissue is obtained, it is most unlikely thatmalignancyexists.2003-10-27Carcinomaofthe Endometrium11
2003-10-27 Carcinoma of the Endometrium 11 Diagnosis Hysteroscopy with endometrial curettage or endometrial sampling，curettage alone， or outpatient endometrial sampling alone， are essential ． Curettage is not infallible．On the other hand，if a Pipelle has been correctly introduced（record how many cm）and the pathology is benign, or no tissue is obtained，it is most unlikely that malignancy exists．
Hysteroscopy, cervical smear (>1%risk of concurrent cervical malignancyand vaginal or abdominal ultrasoundfor ovarian pathology are advised,whenendometrial malignancyisfound.2003-10-27Carcinomaof the Endometrium12
2003-10-27 Carcinoma of the Endometrium 12 Hysteroscopy，cervical smear（>1％ risk of concurrent cervical malignancy） and vaginal or abdominal ultrasound for ovarian pathology are advised， when endometrial malignancy is found．
CurettageHysteroscopyS1
2003-10-27 Carcinoma of the Endometrium 13
TypicalearlypolypoidalfundalgrowthHistologyThe majority of tumours (60%) are pure adenocarcinomata. They can be divided into3 groups according to the degree of glandular differentiation
2003-10-27 Carcinoma of the Endometrium 14
Grade 1welldifferentiatedGland forms are conspicuous. Mitoticfigures are moderately numerous.Grade 2- patchy differentiationGland forms are much less prominentSingleand many deposits consist ofcellinfiltrating single cell columnscolumnsor solid masses.Grade 3. This type consists of solidmasses of malignant cells ofvaryingsizes and shapes with little or no stroma.Mitoses arenumerous
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